N²,O^5'-ditrityl-9-(2-O-acetyl-β-D-arabinofuranosyl)-2-amino-6-chloropurine

Base Information

Chemical Name:N²,O^5'-ditrityl-9-(2-O-acetyl-β-D-arabinofuranosyl)-2-amino-6-chloropurine
CAS No.:514830-07-0
Molecular Formula:C₅₀H₄₂ClN₅O₅
Molecular Weight:828.367
Hs Code.:

N<sup>2</sup>,O<sup>5'</sup>-ditrityl-9-(2-O-acetyl-β-D-arabinofuranosyl)-2-amino-6-chloropurine

Synonyms:N²,O^5'-ditrityl-9-(2-O-acetyl-β-D-arabinofuranosyl)-2-amino-6-chloropurine

Suppliers and Price of N²,O^5'-ditrityl-9-(2-O-acetyl-β-D-arabinofuranosyl)-2-amino-6-chloropurine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N²,O^5'-ditrityl-9-(2-O-acetyl-β-D-arabinofuranosyl)-2-amino-6-chloropurine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N²,O^5'-ditrityl-9-(2-O-acetyl-β-D-arabinofuranosyl)-2-amino-6-chloropurine

There total 5 articles about N²,O^5'-ditrityl-9-(2-O-acetyl-β-D-arabinofuranosyl)-2-amino-6-chloropurine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 76-83-5
trityl chloride

: 514830-11-6
9-(2-O-acetyl-β-D-arabinofuranosyl)-2-amino-6-chloropurine

: 514830-07-0
N²,O^5'-ditrityl-9-(2-O-acetyl-β-D-arabinofuranosyl)-2-amino-6-chloropurine

Guidance literature:: With dmap; triethylamine; In N,N-dimethyl-formamide; at 50 ℃;
DOI:10.1081/NCN-120016479

Reference yield:

: 2004-07-1
2-Amino-6-chloropurine riboside

: 514830-07-0
N²,O^5'-ditrityl-9-(2-O-acetyl-β-D-arabinofuranosyl)-2-amino-6-chloropurine

Guidance literature:: Multi-step reaction with 5 steps

1: imidazole / dimethylformamide

2: Et₃N; DMAP / CH₂Cl₂ / 0.17 h / 20 °C

3: 13.4 g / dimethylformamide / 10 h / 50 °C

4: 93 percent / TBAF; AcOH / tetrahydrofuran / 2 h / 20 °C

5: 69 percent / DMAP; Et₃N / dimethylformamide / 50 °C

With 1H-imidazole; dmap; tetrabutyl ammonium fluoride; acetic acid; triethylamine; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1081/NCN-120016479

Reference yield:

: 87791-91-1
2-amino-6-chloro-9-[3,5-O-(tetraisopropyldisiloxane-1,3-diyl)-β-D-ribofuranosyl]purine

: 514830-07-0
N²,O^5'-ditrityl-9-(2-O-acetyl-β-D-arabinofuranosyl)-2-amino-6-chloropurine

Guidance literature:: Multi-step reaction with 4 steps

1: Et₃N; DMAP / CH₂Cl₂ / 0.17 h / 20 °C

2: 13.4 g / dimethylformamide / 10 h / 50 °C

3: 93 percent / TBAF; AcOH / tetrahydrofuran / 2 h / 20 °C

4: 69 percent / DMAP; Et₃N / dimethylformamide / 50 °C

With dmap; tetrabutyl ammonium fluoride; acetic acid; triethylamine; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1081/NCN-120016479