2-Ethynylthiophene

Base Information

Chemical Name:2-Ethynylthiophene
CAS No.:4298-52-6
Molecular Formula:C6H4S
Molecular Weight:108.164
Hs Code.:29349990
European Community (EC) Number:801-598-3
DSSTox Substance ID:DTXSID40412961
Nikkaji Number:J570.586J
Wikidata:Q72477893
Mol file:4298-52-6.mol

Synonyms:2-Ethynylthiophene;4298-52-6;2-ethynyl-thiophene;2-Acetylenylthiophene;MFCD03425129;2-thienylethine;2-thiophenylacetylene;(2-Thienyl)acetylene;(thiophen-2-yl)acetylene;2-ethynylthiophene, 90%;SCHEMBL168703;2-ethynylthiophene, AldrichCPR;DTXSID40412961;CHEBI:167071;LWISLHRIEATKTM-UHFFFAOYSA-N;AMY15557;AKOS010651593;CS-W011286;PS-9283;SB66967;SY021631;E0915;FT-0645320;EN300-199717;A826100;J-509349

Suppliers and Price of 2-Ethynylthiophene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Ethynylthiophene
100mg
$ 75.00

TCI Chemical
2-Ethynylthiophene >96.0%(GC)
1g
$ 79.00

TCI Chemical
2-Ethynylthiophene >96.0%(GC)
5g
$ 271.00

Synthonix
2-Ethynylthiophene 95%
25g
$ 460.00

Synthonix
2-Ethynylthiophene 95%
10g
$ 200.00

Synthonix
2-Ethynylthiophene 95%
5g
$ 100.00

Synthonix
2-Ethynylthiophene 95%
1g
$ 30.00

Synthonix
2-Ethynylthiophene 95%
250mg
$ 30.00

SynQuest Laboratories
2-Ethynylthiophene 95.0%
1 g
$ 61.00

SynQuest Laboratories
2-Ethynylthiophene 95.0%
5 g
$ 223.00

Total 68 raw suppliers

Chemical Property of 2-Ethynylthiophene

Chemical Property:

Vapor Pressure:5mmHg at 25°C
Refractive Index:1.571
Boiling Point:150 °C at 760 mmHg
Flash Point:28.4 °C
PSA：28.24000
Density:1.11 g/cm³
LogP:1.72940
Storage Temp.:Store Cold
XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:108.00337130
Heavy Atom Count:7
Complexity:98

Purity/Quality:

99% ^*data from raw suppliers

2-Ethynylthiophene ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 10-36/37/38-36
Safety Statements: 16-23-26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C#CC1=CC=CS1
Uses 2-Ethynylthiophene is used in preparation of triazole derivative as Hsp90 inhibitors and anti-cancer metastasis drugs.

Technology Process of 2-Ethynylthiophene

There total 1 articles about 2-Ethynylthiophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 188290-36-0,8014-23-1,25233-34-5
thiophene

: 4298-52-6
2-ethynyl-thiophene

: 2944-05-0,767590-23-8
carbon monosulfide

: 18282-77-4
thioketene

: 536-74-3
phenylacetylene

Guidance literature:: Further byproducts given. Title compound not separated from byproducts; 1.) glow discharge, 2.) -196 deg C -> -80 deg C;

Reference yield: 99.0%

: 4298-52-6
2-ethynyl-thiophene

: 16900-51-9
1,4-bis(2-thienyl)butadiyne

Guidance literature:: With [2,2]bipyridinyl; oxygen; copper(l) chloride; In N,N-dimethyl-formamide; at 20 ℃; for 2h;
DOI:10.1246/cl.140944

Reference yield: 95.0%

: 4298-52-6
2-ethynyl-thiophene

: 88-15-3,97511-16-5
2-Acetylthiophene

Guidance literature:: With indium(III) triflate; water; toluene-4-sulfonic acid; In 1,2-dichloro-ethane; for 0.3h; regioselective reaction; Sealed tube; Reflux;
DOI:10.1016/j.tet.2013.03.079