Technology Process of C19H30O5
There total 9 articles about C19H30O5 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetrabutyl ammonium fluoride;
In
tetrahydrofuran;
at 0 - 20 ℃;
for 3h;
Inert atmosphere;
DOI:10.1021/ol5008179
- Guidance literature:
-
Multi-step reaction with 7 steps
1: tetramethylammonium triacetoxyborohydride / acetonitrile; acetic acid / 24 h / -40 - -30 °C / Inert atmosphere
2: camphor-10-sulfonic acid / dichloromethane; methanol / 4 h / 0 - 20 °C / Inert atmosphere
3: camphor-10-sulfonic acid / dichloromethane; methanol / 2 h / 0 °C / Inert atmosphere
4: Proton-sponge / dichloromethane / 6 h / 0 - 20 °C / Inert atmosphere
5: diisobutylaluminium hydride / dichloromethane; toluene / -10 °C / Inert atmosphere
6: Dess-Martin periodane / dichloromethane; tert-butyl alcohol / 0 - 20 °C / Inert atmosphere
7: tetrabutyl ammonium fluoride / tetrahydrofuran / 3 h / 0 - 20 °C / Inert atmosphere
With
camphor-10-sulfonic acid; tetrabutyl ammonium fluoride; diisobutylaluminium hydride; Dess-Martin periodane; tetramethylammonium triacetoxyborohydride;
In
tetrahydrofuran; methanol; dichloromethane; acetic acid; toluene; acetonitrile; tert-butyl alcohol;
DOI:10.1021/ol5008179
- Guidance literature:
-
Multi-step reaction with 9 steps
1: triethylamine / diethyl ether / 0 - 20 °C / Inert atmosphere
2: boron trifluoride diethyl etherate / dichloromethane / -95 - -78 °C / Inert atmosphere
3: tetramethylammonium triacetoxyborohydride / acetonitrile; acetic acid / 24 h / -40 - -30 °C / Inert atmosphere
4: camphor-10-sulfonic acid / dichloromethane; methanol / 4 h / 0 - 20 °C / Inert atmosphere
5: camphor-10-sulfonic acid / dichloromethane; methanol / 2 h / 0 °C / Inert atmosphere
6: Proton-sponge / dichloromethane / 6 h / 0 - 20 °C / Inert atmosphere
7: diisobutylaluminium hydride / dichloromethane; toluene / -10 °C / Inert atmosphere
8: Dess-Martin periodane / dichloromethane; tert-butyl alcohol / 0 - 20 °C / Inert atmosphere
9: tetrabutyl ammonium fluoride / tetrahydrofuran / 3 h / 0 - 20 °C / Inert atmosphere
With
camphor-10-sulfonic acid; boron trifluoride diethyl etherate; tetrabutyl ammonium fluoride; diisobutylaluminium hydride; Dess-Martin periodane; triethylamine; tetramethylammonium triacetoxyborohydride;
In
tetrahydrofuran; methanol; diethyl ether; dichloromethane; acetic acid; toluene; acetonitrile; tert-butyl alcohol;
2: |Mukaiyama Aldol Addition;
DOI:10.1021/ol5008179