2-[3-(tert-butyl-diphenyl-silanyloxy)-prop-1-ynyl]-furan-3-carbaldehyde

Base Information

• Chemical Name: 2-[3-(tert-butyl-diphenyl-silanyloxy)-prop-1-ynyl]-furan-3-carbaldehyde
• CAS No.: 911710-57-1
• Molecular Formula: C₂₄H₂₄O₃Si
• Molecular Weight: 388.538
• Mol file: 911710-57-1.mol

Synonyms:2-[3-(tert-butyl-diphenyl-silanyloxy)-prop-1-ynyl]-furan-3-carbaldehyde

Chemical Property of 2-[3-(tert-butyl-diphenyl-silanyloxy)-prop-1-ynyl]-furan-3-carbaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-[3-(tert-butyl-diphenyl-silanyloxy)-prop-1-ynyl]-furan-3-carbaldehyde

There total 4 articles about 2-[3-(tert-butyl-diphenyl-silanyloxy)-prop-1-ynyl]-furan-3-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-[3-(tert-butyldiphenylsiloxy)prop-1-ynyl]-3-(2,5-dioxolanyl)furan (870776-84-4) → 2-[3-(tert-butyl-diphenyl-silanyloxy)-prop-1-ynyl]-furan-3-carbaldehyde (911710-57-1)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; at 20 ℃; for 1h;

DOI:10.1016/j.tet.2005.08.088 DOI:10.1021/jo061014b

Reference yield:

2-iodo-furan-3-carbaldehyde → 2-[3-(tert-butyl-diphenyl-silanyloxy)-prop-1-ynyl]-furan-3-carbaldehyde (911710-57-1)

Guidance literature:

Multi-step reaction with 3 steps

1: TsOH / H₂O; benzene / 1.5 h / Heating

2: 4.49 g / triethylamine; CuI / Pd(PPh₃)2Cl₂ / tetrahydrofuran / 20 °C

3: aq. HCl / tetrahydrofuran / 1 h / 20 °C

With hydrogenchloride; copper(l) iodide; toluene-4-sulfonic acid; triethylamine; bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran; water; benzene;

DOI:10.1016/j.tet.2005.08.088

Reference yield:

2-iodo-3-(1,3-dioxolan-2-yl)furan → 2-[3-(tert-butyl-diphenyl-silanyloxy)-prop-1-ynyl]-furan-3-carbaldehyde (911710-57-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 4.49 g / triethylamine; CuI / Pd(PPh₃)2Cl₂ / tetrahydrofuran / 20 °C

2: aq. HCl / tetrahydrofuran / 1 h / 20 °C

With hydrogenchloride; copper(l) iodide; triethylamine; bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran;

DOI:10.1016/j.tet.2005.08.088

upstream raw materials:

2-[3-(tert-butyldiphenylsiloxy)prop-1-ynyl]-3-(2,5-dioxolanyl)furan

furan-3-carboxaldehyde

Downstream raw materials:

2-[3-(tert-butyldiphenylsiloxy)prop-1-ynyl]-3-[1-hydroxy-5-(trimethylsilyl)pent-4-ynyl]furan

tert-butyl-{3-[3-(2,2-dibromo-vinyl)-furan-2-yl]-prop-2-ynyloxy}-diphenyl-silane

3-{2-[3-(tert-butyl-diphenyl-silanyloxy)-prop-1-ynyl]-furan-3-yl}-prop-2-yn-1-ol

2-(3-hydroxyprop-1-ynyl)-3-[1-(methoxymethoxy)-5-phenylpent-4-ynyl]furan