28-O-trityl-3β-(tert-butyldimethylsilyloxy)-2α-hydroxylup-20(29)-en-28-ol

Base Information

• Chemical Name: 28-O-trityl-3β-(tert-butyldimethylsilyloxy)-2α-hydroxylup-20(29)-en-28-ol
• CAS No.: 1190957-63-1
• Molecular Formula: C₅₅H₇₈O₃Si
• Molecular Weight: 815.308
• Mol file: 1190957-63-1.mol

Synonyms:28-O-trityl-3β-(tert-butyldimethylsilyloxy)-2α-hydroxylup-20(29)-en-28-ol

Chemical Property of 28-O-trityl-3β-(tert-butyldimethylsilyloxy)-2α-hydroxylup-20(29)-en-28-ol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 28-O-trityl-3β-(tert-butyldimethylsilyloxy)-2α-hydroxylup-20(29)-en-28-ol

There total 1 articles about 28-O-trityl-3β-(tert-butyldimethylsilyloxy)-2α-hydroxylup-20(29)-en-28-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

28-O-trityl-3β-(tert-butyldimethylsilyloxy)lup-20(29)-en-28-ol-2-one (1190957-62-0) → 28-O-trityl-3β-(tert-butyldimethylsilyloxy)-2β-hydroxylup-20(29)-en-28-ol + 28-O-trityl-3β-(tert-butyldimethylsilyloxy)-2α-hydroxylup-20(29)-en-28-ol (1190957-63-1)

Guidance literature:

28-O-trityl-3β-(tert-butyldimethylsilyloxy)lup-20(29)-en-28-ol-2-one; With aluminum (III) chloride; aluminum isopropoxide; In isopropyl alcohol; at 110 ℃; for 120h;

With hydrogenchloride; water; at 0 ℃; pH=3;

DOI:10.1016/j.tet.2009.07.047

Reference yield: 94.0%

28-O-trityl-3β-(tert-butyldimethylsilyloxy)-2α-hydroxylup-20(29)-en-28-ol (1190957-63-1) → 28-O-trityl-2α,3β-dihydroxylup-20(29)-en-28-ol (1190957-64-2)

Guidance literature:

With tetrabutyl ammonium fluoride; water; In tetrahydrofuran; for 2h; Reflux;

DOI:10.1016/j.tet.2009.07.047

upstream raw materials:

28-O-trityl-3β-(tert-butyldimethylsilyloxy)lup-20(29)-en-28-ol-2-one

Downstream raw materials:

28-O-trityl-2α,3β-dihydroxylup-20(29)-en-28-ol