3-(3,4-dimethoxyphenyl)-8,8-dimethyl-4-oxo-4H,8H-benzo[1,2-b:3,4-b']dipyran

Base Information

• Chemical Name: 3-(3,4-dimethoxyphenyl)-8,8-dimethyl-4-oxo-4H,8H-benzo[1,2-b:3,4-b']dipyran
• CAS No.: 63286-38-4
• Molecular Formula: C₂₂H₂₀O₅
• Molecular Weight: 364.398
• Mol file: 63286-38-4.mol

Synonyms:3-(3,4-dimethoxyphenyl)-8,8-dimethyl-4-oxo-4H,8H-benzo[1,2-b:3,4-b']dipyran

Chemical Property of 3-(3,4-dimethoxyphenyl)-8,8-dimethyl-4-oxo-4H,8H-benzo[1,2-b:3,4-b']dipyran

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(3,4-dimethoxyphenyl)-8,8-dimethyl-4-oxo-4H,8H-benzo[1,2-b:3,4-b']dipyran

There total 23 articles about 3-(3,4-dimethoxyphenyl)-8,8-dimethyl-4-oxo-4H,8H-benzo[1,2-b:3,4-b']dipyran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-(3,4-dimethoxyphenyl)-1-(5-hydroxy-2,2-dimethyl-2H-chromen-6-yl)-2-(phenylsulfonyl)ethanone (63286-36-2) + N,N-dimethyl-formamide dimethyl acetal (4637-24-5) → 3-(3,4-dimethoxyphenyl)-8,8-dimethyl-4-oxo-4H,8H-benzo[1,2-b:3,4-b']dipyran (63286-38-4)

Guidance literature:

In toluene; for 2h; Reflux;

Reference yield: 73.4%

3-iodo-8,8-dimethylpyrano[2,3-f]chromen-4(8H)-one (1422513-84-5) + 3,4-Dimethoxyphenylboronic acid (122775-35-3) → 3-(3,4-dimethoxyphenyl)-8,8-dimethyl-4-oxo-4H,8H-benzo[1,2-b:3,4-b']dipyran (63286-38-4)

Guidance literature:

With palladium 10% on activated carbon; sodium carbonate; In 1,2-dimethoxyethane; water; at 45 ℃; for 1h;

DOI:10.1016/j.bioorg.2019.102949

Reference yield:

C24H28O7 → 3-(3,4-dimethoxyphenyl)-8,8-dimethyl-4-oxo-4H,8H-benzo[1,2-b:3,4-b']dipyran (63286-38-4)

Guidance literature:

With hydrogenchloride; In methanol; water; for 6h; Reflux;

DOI:10.1016/j.fitote.2014.06.002

upstream raw materials:

7-hydroxy-3-iodo-4H-chromen-4-one

3-iodo-8,8-dimethylpyrano[2,3-f]chromen-4(8H)-one

3,4-Dimethoxyphenylboronic acid

1,1-diethoxy-3-methyl-2-butene