Ethyl 7-(benzyloxy)-4-hydroxyquinoline-3-carboxylate

Base Information

Chemical Name:Ethyl 7-(benzyloxy)-4-hydroxyquinoline-3-carboxylate
CAS No.:17825-15-9
Molecular Formula:C19H17 N O4
Molecular Weight:323.348
Hs Code.:2933499090
ChEMBL ID:CHEMBL3219632
DSSTox Substance ID:DTXSID10594829
Nikkaji Number:J665.041D
Wikidata:Q82489739
Mol file:17825-15-9.mol

Synonyms:17825-15-9;Ethyl 7-(benzyloxy)-4-hydroxyquinoline-3-carboxylate;ethyl 4-oxo-7-phenylmethoxy-1H-quinoline-3-carboxylate;24358-37-0;7-BENZYLOXY-4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER;Ethyl 7-(benzyloxy)-4-oxo-1,4-dihydroquinoline-3-carboxylate;AJFAAXMCFXOPOM-UHFFFAOYSA-N;Ethyl 4-oxo-7-(benzyloxy)hydroquinoline-3-carboxylate;SCHEMBL4176704;CHEMBL3219632;DTXSID10594829;ethyl 7-benzyloxy-4-oxo-1,4-dihydro-quinoline-3-carboxylate;MFCD03839743;AKOS015910342;AKOS022168625;SB72839;MS-10840;DB-369444;F11932;Ethyl7-(benzyloxy)-4-hydroxyquinoline-3-carboxylate;3-Quinolinecarboxylicacid,4-hydroxy-7-(phenylmethoxy)-,ethyl ester;7-benzyloxy-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid ethyl ester

Suppliers and Price of Ethyl 7-(benzyloxy)-4-hydroxyquinoline-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Ethyl7-(benzyloxy)-4-hydroxyquinoline-3-carboxylate 97%
1g
$ 653.00

Chemenu
Ethyl7-(benzyloxy)-4-hydroxyquinoline-3-carboxylate 97%
1g
$ 617.00

American Custom Chemicals Corporation
7-BENZYLOXY-4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER 95.00%
5G
$ 918.11

Total 28 raw suppliers

Chemical Property of Ethyl 7-(benzyloxy)-4-hydroxyquinoline-3-carboxylate

Chemical Property:

Vapor Pressure:8.69E-10mmHg at 25°C
Boiling Point:491°C at 760 mmHg
Flash Point:250.8°C
PSA：68.65000
Density:1.248g/cm³
LogP:3.69610
XLogP3:3.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:323.11575802
Heavy Atom Count:24
Complexity:496

Purity/Quality:

99% ^*data from raw suppliers

Ethyl7-(benzyloxy)-4-hydroxyquinoline-3-carboxylate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CNC2=C(C1=O)C=CC(=C2)OCC3=CC=CC=C3

Technology Process of Ethyl 7-(benzyloxy)-4-hydroxyquinoline-3-carboxylate

There total 4 articles about Ethyl 7-(benzyloxy)-4-hydroxyquinoline-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 17825-16-0
diethyl <<3-(benzyloxy)anilino>methylene>malonate

: 17825-15-9
ethyl 7-(benzyloxy)-4-quinolone-3-carboxylate

Guidance literature:: In diphenylether; for 0.5h; Heating;
DOI:10.1021/jm00006a014

Reference yield:

: 1484-26-0
3-(benzyloxy)aniline

: 17825-15-9
ethyl 7-(benzyloxy)-4-quinolone-3-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 2 h / Heating

2: 74 percent / diphenyl ether / 0.5 h / Heating

In diphenylether;
DOI:10.1021/jm00006a014

Reference yield:

: 87-13-8
diethyl 2-ethoxymethylenemalonate

: 17825-15-9
ethyl 7-(benzyloxy)-4-quinolone-3-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 2 h / Heating

2: 74 percent / diphenyl ether / 0.5 h / Heating

In diphenylether;
DOI:10.1021/jm00006a014