BIS(4-METHYLPHENYL)CHLOROPHOSPHINE

Base Information

• Chemical Name: BIS(4-METHYLPHENYL)CHLOROPHOSPHINE
• CAS No.: 13685-23-9
• Molecular Formula: C14H14 Cl P
• Molecular Weight: 248.692
• Hs Code.: 2903999090
• Mol file: 13685-23-9.mol

Synonyms:Phosphinouschloride, bis(3-methylphenyl)- (9CI); Phosphinous chloride, di-m-tolyl- (8CI);Chlorobis(3-methylphenyl)phosphine; Di-(m-Methylphenyl)phosphine chloride

Chemical Property of BIS(4-METHYLPHENYL)CHLOROPHOSPHINE

Chemical Property:

• Refractive Index: n20/D 1.501
• Boiling Point: 180-184℃/10mm
• Flash Point: 180-184℃/10mm
• PSA: 13.59000
• Density: 1.159
• LogP: 3.88990
• Sensitive.: Moisture Sensitive

Purity/Quality:

99% ^*data from raw suppliers

Bis(4-methylphenyl)chlorophosphine 96% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Statements: 14-34
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of BIS(4-METHYLPHENYL)CHLOROPHOSPHINE

There total 3 articles about BIS(4-METHYLPHENYL)CHLOROPHOSPHINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

bis(3-methylphenyl)phosphine oxide (145290-34-2) → chloro-di-(3-methylphenyl)phosphine (13685-23-9)

Guidance literature:

With phosphorus trichloride; In toluene; at 0 - 10 ℃; for 0.5h; Inert atmosphere;

DOI:10.1002/adsc.201800103

Reference yield:

meta-bromotoluene (591-17-3) → chloro-di-(3-methylphenyl)phosphine (13685-23-9)

Guidance literature:

meta-bromotoluene; With tert.-butyl lithium; In cyclohexane; pentane; at 0 - 20 ℃; for 15h;

In diethyl ether; at 20 ℃; for 1h; Further stages.;

DOI:10.1002/adsc.200600503

Reference yield:

→ chloro-di-(3-methylphenyl)phosphine (13685-23-9)

Guidance literature:

m-Methylchlorbenzol, P, AlCl3;

DOI:10.1021/jo00912a027

upstream raw materials:

meta-bromotoluene

bis(3-methylphenyl)phosphine oxide

Downstream raw materials:

(4R,5R)-trans-4,5-bis(((3-methylphenyl)phosphino)-methyl)-2,2-dimethyl-1,3-dioxolane

(R)-(2-(tert-butylsulfinyl)phenyl)di-m-tolylphosphine

Refernces

• 1、 Liu, Teng,Sun, Xue,Wu, Lei. "Palladium-Catalyzed Cascade C?O Cleavage and C?H Alkenylation of Phosphinyl Allenes: An Expeditious Approach to 3-Alkenyl Benzo[b]phosphole Oxides". supporting information. p. 2005 - 2012. Retrieved 2018/03/27.