Magnesium chlorobenzene bromide

Base Information

• Chemical Name: Magnesium chlorobenzene bromide
• CAS No.: 36229-42-2
• Molecular Formula: C6H4BrClMg
• Molecular Weight: 215.76
• Hs Code.: 29319090
• DSSTox Substance ID: DTXSID80482542
• Mol file: 36229-42-2.mol

Synonyms:magnesium chlorobenzene bromide;magnesium chloranylbenzene bromide;DTXSID80482542;Magnesium 3-chlorobenzen-1-ide bromide;CS-0451692;A842117

Chemical Property of Magnesium chlorobenzene bromide

Chemical Property:

• Boiling Point: 65 °C(lit.)
• Flash Point: 1 °F
• PSA: 0.00000
• Density: 0.960 g/mL at 25 °C(lit.)
• LogP: 2.98580
• Storage Temp.: 2-8°C
• Sensitive.: Air & Moisture Sensitive
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 213.90353
• Heavy Atom Count: 9
• Complexity: 140

Purity/Quality:

99.0% ^*data from raw suppliers

3-Chlorophenylmagnesium bromide 0.5 M in THF ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F,C,F+
• Hazard Codes: F,C,F+,Xn
• Statements: 11-14-19-22-34-40-12-36/37
• Safety Statements: 16-23-26-36/37/39-45-36/37

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C[C-]=CC(=C1)Cl.[Mg+2].[Br-]
• Uses: 3-Chlorophenylmagnesium bromide is involved in the synthesis of enantiopure 2-imidazolidinones by reacting with 1,1'-DiBoc-2,2'-Biaziridine.

Technology Process of Magnesium chlorobenzene bromide

There total 1 articles about Magnesium chlorobenzene bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-bromo-3-chlorobenzene (108-37-2) → (3-chlorophenyl)magnesium bromide (36229-42-2)

Guidance literature:

With iodine; In diethyl ether;

Reference yield: 93.0%

N,N,N-trimethylbenzeneaminium trifluoromethanesulfonate + (3-chlorophenyl)magnesium bromide (36229-42-2) → m-chlorobiphenyl (2051-61-8)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran; at 20 ℃; for 1h; Inert atmosphere;

DOI:10.1021/ol1018739

Reference yield: 89.0%

Methyl 3-formylbenzoate (52178-50-4) + (3-chlorophenyl)magnesium bromide (36229-42-2) → methyl 3-[(3-chlorophenyl)(hydroxy)methyl]benzoate (1093865-16-7)

Guidance literature:

Methyl 3-formylbenzoate; (3-chlorophenyl)magnesium bromide; In tetrahydrofuran; diethyl ether; at 0 ℃; for 1.5h;

With sodium hydrogencarbonate; In tetrahydrofuran; diethyl ether; water;

upstream raw materials:

1-bromo-3-chlorobenzene

Downstream raw materials:

2-(3-chloro-benzoyl)-[1]naphthoic acid

(3-chloro-phenyl)-(1-methyl-[4]piperidyl)-phenyl-methanol

1-(m-Chlorophenyl)ethanol

2,2,2-trichloro-1-(3-chlorophenyl)ethan-1-ol

Refernces

• 1、 -. "Platinum complex and light-emitting device". Page/Page column 30-31. . Retrieved 2010/11/23.