5-Chloro-2-morpholin-4-yl-phenylamine

Base Information

Chemical Name:5-Chloro-2-morpholin-4-yl-phenylamine
CAS No.:90875-44-8
Molecular Formula:C10H13ClN2O
Molecular Weight:212.679
Hs Code.:
European Community (EC) Number:858-087-3
DSSTox Substance ID:DTXSID60357168
Wikidata:Q82136949
ChEMBL ID:CHEMBL1539547
Mol file:90875-44-8.mol

Synonyms:90875-44-8;5-Chloro-2-morpholinoaniline;5-Chloro-2-morpholin-4-yl-phenylamine;5-chloro-2-morpholin-4-ylaniline;5-chloro-2-(morpholin-4-yl)aniline;5-chloro-2-morpholin-4-yl-aniline;(5-chloro-2-morpholin-4-ylphenyl)amine;MLS000048848;5-chloro-2-morpholin-4-ylphenylamine;Benzenamine, 5-chloro-2-(4-morpholinyl)-;SCHEMBL3724717;CHEMBL1539547;DTXSID60357168;UNDBLGNMBLCRNJ-UHFFFAOYSA-N;HMS2318B04;MFCD02934447;STK141093;4-(2-amino-4-chlorophenyl)morpholine;AKOS000103419;5-chloro-2-(4-morpholinyl)phenylamine;SMR000062514;BB 0245141;FT-0677118;EN300-34073;AO-080/15281003;BENZENAMINE,5-CHLORO-2-(4-MORPHOLINYL)-;SR-01000535005;5-chloro-2-morpholin-4-yl-phenylamine, AldrichCPR;SR-01000535005-1;Z56896791

Suppliers and Price of 5-Chloro-2-morpholin-4-yl-phenylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-chloro-2-morpholin-4-ylaniline
100mg
$ 90.00

Matrix Scientific
5-Chloro-2-morpholin-4-yl-phenylamine
1g
$ 283.00

Matrix Scientific
5-Chloro-2-morpholin-4-yl-phenylamine
500mg
$ 184.00

Crysdot
5-Chloro-2-morpholinoaniline 95+%
250mg
$ 58.00

Crysdot
5-Chloro-2-morpholinoaniline 95+%
1g
$ 146.00

Biosynth Carbosynth
(5-Chloro-2-morpholin-4-ylphenyl)amine
500 mg
$ 100.00

Biosynth Carbosynth
(5-Chloro-2-morpholin-4-ylphenyl)amine
250 mg
$ 57.50

Biosynth Carbosynth
(5-Chloro-2-morpholin-4-ylphenyl)amine
1 g
$ 170.00

Biosynth Carbosynth
(5-Chloro-2-morpholin-4-ylphenyl)amine
5 g
$ 578.00

Biosynth Carbosynth
(5-Chloro-2-morpholin-4-ylphenyl)amine
2 g
$ 289.00

Total 18 raw suppliers

Chemical Property of 5-Chloro-2-morpholin-4-yl-phenylamine

Chemical Property:

Vapor Pressure:4.08E-06mmHg at 25°C
Refractive Index:1.6
Boiling Point:384.5 °C at 760 mmHg
Flash Point:186.3 °C
PSA：38.49000
Density:1.273g/cm³
LogP:2.40500
Storage Temp.:2-8°C(protect from light)
XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:212.0716407
Heavy Atom Count:14
Complexity:185

Purity/Quality:

97% ^*data from raw suppliers

5-chloro-2-morpholin-4-ylaniline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1COCCN1C2=C(C=C(C=C2)Cl)N

Technology Process of 5-Chloro-2-morpholin-4-yl-phenylamine

There total 2 articles about 5-Chloro-2-morpholin-4-yl-phenylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 65976-60-5
4-(4-chloro-2-nitro-phenyl)morpholine

: 90875-44-8
5-chloro-2-morpholinoaniline

Guidance literature:: With hydrogenchloride; ethanol; iron;
DOI:10.1039/jr9550003275

Reference yield:

: 345-18-6
2-fluoro-5-chloronitrobenzene

: 90875-44-8
5-chloro-2-morpholinoaniline

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 4 h / 0 - 80 °C

2: zinc; ammonium chloride / ethanol / 16 h / Inert atmosphere; Reflux

With potassium carbonate; ammonium chloride; zinc; In ethanol; N,N-dimethyl-formamide;
DOI:10.1016/j.bioorg.2021.105244

Reference yield: 50.0%

: 90875-44-8
5-chloro-2-morpholinoaniline

: 100-51-6,185532-71-2
benzyl alcohol

: 5-chloro-N-(1,2-diphenylethyl)-2-morpholinoaniline

Guidance literature:: With palladium diacetate; sodium 3-(diphenylphosphanyl)benzenesulfonate; In water; at 120 ℃; for 20h; chemoselective reaction; Sealed tube; Green chemistry;
DOI:10.1039/c7gc03780e