5-[1-(4-bromophenyl)-1,2-dimethyl-propyl]-3-(3-pyridyl)-1,2,4-oxadiazole

Base Information

Chemical Name:5-[1-(4-bromophenyl)-1,2-dimethyl-propyl]-3-(3-pyridyl)-1,2,4-oxadiazole
CAS No.:1448612-48-3
Molecular Formula:C₁₈H₁₈BrN₃O
Molecular Weight:372.264
Hs Code.:

Synonyms:5-[1-(4-bromophenyl)-1,2-dimethyl-propyl]-3-(3-pyridyl)-1,2,4-oxadiazole

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Chemical Property of 5-[1-(4-bromophenyl)-1,2-dimethyl-propyl]-3-(3-pyridyl)-1,2,4-oxadiazole

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Technology Process of 5-[1-(4-bromophenyl)-1,2-dimethyl-propyl]-3-(3-pyridyl)-1,2,4-oxadiazole

There total 3 articles about 5-[1-(4-bromophenyl)-1,2-dimethyl-propyl]-3-(3-pyridyl)-1,2,4-oxadiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1382486-65-8
C₁₇H₁₇BrN₄O₂

: 1594-58-7
(Z)-N'-hydroxy(pyridin-3-yl)methanimidamide

: 1448612-48-3
5-[1-(4-bromophenyl)-1,2-dimethyl-propyl]-3-(3-pyridyl)-1,2,4-oxadiazole

Guidance literature:: With PS-BEMP; at 120 ℃; for 0.5h; Microwave irradiation;

Reference yield:

: 1382486-58-9
2-(4-bromophenyl)-2,3-dimethylbutanoic acid

: 1448612-48-3
5-[1-(4-bromophenyl)-1,2-dimethyl-propyl]-3-(3-pyridyl)-1,2,4-oxadiazole

Guidance literature:: Multi-step reaction with 2 steps

1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 0.5 h / 20 °C

2: PS-BEMP / 0.5 h / 120 °C / Microwave irradiation

With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide;

Reference yield:

: 1360551-87-6
2-(4-bromo-phenyl)-2,3-dimethylbutyronitrile

: 1448612-48-3
5-[1-(4-bromophenyl)-1,2-dimethyl-propyl]-3-(3-pyridyl)-1,2,4-oxadiazole

Guidance literature:: Multi-step reaction with 3 steps

1: sulfuric acid; hydrogen bromide / water / 52 h / 110 - 145 °C

2: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 0.5 h / 20 °C

3: PS-BEMP / 0.5 h / 120 °C / Microwave irradiation

With sulfuric acid; hydrogen bromide; N-ethyl-N,N-diisopropylamine; In water; N,N-dimethyl-formamide;