Tert-butyl 6,7-dihydrothiazolo[5,4-C]pyridine-5(4H)-carboxylate

Base Information

Chemical Name:Tert-butyl 6,7-dihydrothiazolo[5,4-C]pyridine-5(4H)-carboxylate
CAS No.:165948-24-3
Molecular Formula:C₁₁H₁₆N₂O₂S
Molecular Weight:240.326
Hs Code.:2934999090
DSSTox Substance ID:DTXSID40591225
Wikidata:Q82484953
Mol file:165948-24-3.mol

Synonyms:165948-24-3;TERT-BUTYL 6,7-DIHYDROTHIAZOLO[5,4-C]PYRIDINE-5(4H)-CARBOXYLATE;tert-butyl 6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-5-carboxylate;Thiazolo[5,4-c]pyridine-5(4H)-carboxylic acid, 6,7-dihydro-, 1,1-dimethylethyl ester;AUHQOOIWUXNGES-UHFFFAOYSA-N;SCHEMBL741598;5-Boc-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine;DTXSID40591225;MFCD08234810;AKOS015841235;BS-21675;5-BOC-6,7-dihydrothiazolo[5,4-c]pyridine;CS-0135369;A849530;J-524751;5-tert-Butoxycarbonyl-4,5,6,7-tetrahydrothiazolo[5,4-c]-pyridine;5-tert-butoxycarbonyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine;TERT-BUTYL 4H,6H,7H-[1,3]THIAZOLO[5,4-C]PYRIDINE-5-CARBOXYLATE;tert-Butyl 6,7-dihydro[1,3]thiazolo[5,4-c]pyridine-5(4H)-carboxylate;2-Methyl-2-propanyl 6,7-dihydro[1,3]thiazolo[5,4-c]pyridine-5(4H)-carboxylate;4,5,6,7-Tetrahydro-thiazolo[5,4-c]pyridine-6-carboxylic acid tert-butyl ester;Thiazolo[5,4-c]pyridine-5(4H)-carboxylicacid,6,7-dihydro-,1,1-dimethylethyl ester

Suppliers and Price of Tert-butyl 6,7-dihydrothiazolo[5,4-C]pyridine-5(4H)-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
tert-Butyl6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate 95+%
1g
$ 620.00

American Custom Chemicals Corporation
TERT-BUTYL-6,7-DIHYDROTHIAZOLO[5,4-C]PYRIDINE-5(4H)-CARBOXYLATE 98.00%
5G
$ 2021.25

American Custom Chemicals Corporation
TERT-BUTYL-6,7-DIHYDROTHIAZOLO[5,4-C]PYRIDINE-5(4H)-CARBOXYLATE 98.00%
1G
$ 889.35

Alichem
tert-Butyl6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate
1g
$ 660.00

Alichem
tert-Butyl6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate
5g
$ 2099.86

Alichem
tert-Butyl6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate
250mg
$ 282.48

AK Scientific
tert-Butyl6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate
5g
$ 2451.00

AK Scientific
tert-Butyl6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate
250mg
$ 464.00

Total 21 raw suppliers

Chemical Property of Tert-butyl 6,7-dihydrothiazolo[5,4-C]pyridine-5(4H)-carboxylate

Chemical Property:

Boiling Point:357.5±42.0 °C(Predicted)
PKA:2.90±0.20(Predicted)
PSA：70.67000
Density:1.218±0.06 g/cm3(Predicted)
LogP:2.37420
XLogP3:1.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:240.09324893
Heavy Atom Count:16
Complexity:278

Purity/Quality:

97% ^*data from raw suppliers

tert-Butyl6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCC2=C(C1)SC=N2

Technology Process of Tert-butyl 6,7-dihydrothiazolo[5,4-C]pyridine-5(4H)-carboxylate

There total 9 articles about Tert-butyl 6,7-dihydrothiazolo[5,4-C]pyridine-5(4H)-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.6%

: 365996-06-1
2-Bromo-5-tert-butoxycarbonyl-4,5,6,7-tetrahydro-thiazolo[5,4-c]pyridine

: 165948-24-3
5-tert-Butoxycarbonyl-4,5,6,7-tetrahydrothiazolo[5,4-c]-pyridine

Guidance literature:: With palladium on activated charcoal; hydrogen; potassium hydroxide; In methanol; for 1h;

Reference yield: 36.0%

: 365996-05-0
tert-butyl 2-amino-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate

: 165948-24-3
5-tert-Butoxycarbonyl-4,5,6,7-tetrahydrothiazolo[5,4-c]-pyridine

Guidance literature:: With isopentyl nitrite; In tetrahydrofuran; at 80 ℃; for 2h;

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 165948-24-3
5-tert-Butoxycarbonyl-4,5,6,7-tetrahydrothiazolo[5,4-c]-pyridine

Guidance literature:: 5-Ethoxycarbonyl-4,5,6,7-tetrahydrothiazolo[5,4-c]-pyridine; With sodium hydroxide; water; Heating / reflux;

di-tert-butyl dicarbonate; at 0 - 20 ℃;

With hydrogenchloride; In water; pH=1 - 2;