glycine allyl ester

Base Information

• Chemical Name: glycine allyl ester
• CAS No.: 158840-15-4
• Molecular Formula: C₁₉H₂₆N₂O₅
• Molecular Weight: 362.426
• Mol file: 158840-15-4.mol

Synonyms:glycine allyl ester

Chemical Property of glycine allyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of glycine allyl ester

There total 2 articles about glycine allyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.5%

allyl 2-(4-methylphenylsulfonamido)acetate + N-tert-butoxycarbonyl-L-phenylalanine (13734-34-4) → glycine allyl ester (158840-15-4)

Guidance literature:

With PyBOP; N-ethyl-N,N-diisopropylamine; In chloroform; at 23 ℃; for 2h; Inert atmosphere;

DOI:10.1021/ol301178r

Reference yield: 81.0%

N-tert-butoxycarbonyl-L-phenylalanine (13734-34-4) + p-toluenesulfonic acid salt of glycine allyl ester (88223-98-7) → glycine allyl ester (158840-15-4)

Guidance literature:

With benzotriazol-1-ol; dacarbazine; triethylamine; In dichloromethane; for 12h; Ambient temperature;

DOI:10.1016/S0968-0896(98)00251-X

Reference yield:

glycine allyl ester (158840-15-4) → -2-(2-propenyl)glycine

Guidance literature:

With zinc(II) chloride; lithium diisopropyl amide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; 1.) -78 deg C, 10 min, 2.) r.t., 16 h;

DOI:10.1021/jo00101a026

upstream raw materials:

N-tert-butoxycarbonyl-L-phenylalanine

p-toluenesulfonic acid salt of glycine allyl ester

Downstream raw materials:

2-((2S)-2-((tert-butoxycarbonyl)amino)-3-phenylpropanamido)acetic acid

N-tert-butyloxycarbonyl-L-phenylalanyl-glycyl-L-leucine allyl ester

allyl 2-((S)-2-((2S,3S)-3-methyl-1-tritylaziridine-2-carboxamido)-3-phenylpropanamido)acetate

allyl 2-((S)-2-((2S,3S)-3-methylaziridine-2-carboxamido)-3-phenylpropanamido)acetate