methyl rac-2-isocyano-2-phenylpropionate

Base Information

• Chemical Name: methyl rac-2-isocyano-2-phenylpropionate
• CAS No.: 55610-36-1
• Molecular Formula: C₁₁H₁₁NO₂
• Molecular Weight: 189.214
• Mol file: 55610-36-1.mol

Synonyms:methyl rac-2-isocyano-2-phenylpropionate

Chemical Property of methyl rac-2-isocyano-2-phenylpropionate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of methyl rac-2-isocyano-2-phenylpropionate

There total 3 articles about methyl rac-2-isocyano-2-phenylpropionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

methyl rac-2-benzyl-2-formamidopropionat (2683-73-0) → methyl rac-2-isocyano-2-phenylpropionate (55610-36-1)

Guidance literature:

With pyridine; trichlorophosphate; In chloroform;

Reference yield: 29.0%

methyl cyanoformate (17640-15-2) + 2-((1-isocyano-1-phenylethyl)thio)pyridine + tri-n-butyllithium magnesate complex → 2-pyridyl 1-butyl sulfide (26891-66-7) + methyl rac-2-isocyano-2-phenylpropionate (55610-36-1)

Guidance literature:

2-((1-isocyano-1-phenylethyl)thio)pyridine; tri-n-butyllithium magnesate complex; In tetrahydrofuran; at -78 ℃; for 0.0833333h;

methyl cyanoformate; In tetrahydrofuran; for 0.25h;

Reference yield:

→ methyl rac-2-isocyano-2-phenylpropionate (55610-36-1)

Guidance literature:

Benzylisocyanid (Li + metalliertes Zwischenprodukt);

upstream raw materials:

methyl rac-2-benzyl-2-formamidopropionat

methyl cyanoformate