N-p-Tolyl-N'-p-chlorophenyl thiourea

Base Information

• Chemical Name: N-p-Tolyl-N'-p-chlorophenyl thiourea
• CAS No.: 74322-42-2
• Molecular Formula: C₁₄H₁₃ClN₂S
• Molecular Weight: 276.79
• Mol file: 74322-42-2.mol

Synonyms:N-p-Tolyl-N'-p-chlorophenyl thiourea

Chemical Property of N-p-Tolyl-N'-p-chlorophenyl thiourea

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-p-Tolyl-N'-p-chlorophenyl thiourea

There total 3 articles about N-p-Tolyl-N'-p-chlorophenyl thiourea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.2%

p-toluidine (106-49-0,12221-03-3) + 4-Chlorophenyl isothiocyanate (2131-55-7) → N-p-Tolyl-N'-p-chlorophenyl thiourea (74322-42-2)

Guidance literature:

at 20 ℃;

DOI:10.1081/SCC-100103270

Reference yield: 89.0%

4-chloro-aniline (106-47-8) + 1-isothiocyanato-4-methylbenzene (622-59-3) → N-p-Tolyl-N'-p-chlorophenyl thiourea (74322-42-2)

Guidance literature:

In benzene; Heating;

Reference yield: 87.0%

carbon disulfide (75-15-0,12122-00-8) + p-toluidine (106-49-0,12221-03-3) + 4-chloro-aniline (106-47-8) → N-p-Tolyl-N'-p-chlorophenyl thiourea (74322-42-2)

Guidance literature:

carbon disulfide; p-toluidine; With potassium hydroxide; at 20 ℃; for 0.666667h; Milling; Green chemistry;

4-chloro-aniline; at 20 ℃; for 1h; Milling; Green chemistry;

DOI:10.1039/c3ra43252a

upstream raw materials:

4-chloro-aniline

1-isothiocyanato-4-methylbenzene

p-toluidine

4-Chlorophenyl isothiocyanate

Downstream raw materials:

1-(4-chlorophenyl)-3-p-tolylcarbodiimide

N-[4-(4-chloro-phenyl)-N'-p-tolyl-carbamimidoyl]-N'-isopropyl-thiourea

2-p-Chlorophenylimino-3-p-tolyl-4-thiazolidinone

2-(4-chloro-phenylimino)-5-methyl-3-p-tolyl-thiazolidin-4-one

Refernces

• 1、 Li,Wang,Wang,Luo,Wang. "A new and efficient solid state synthesis of diaryl thioureas". . p. 781 - 785. Retrieved 2007/10/03.