(4S,5S)-5-<(1R)-1-benzoyloxy-2-propen-1-yl>-4-cyanomethyl-2-oxazolidinone

Base Information

Chemical Name:(4S,5S)-5-<(1R)-1-benzoyloxy-2-propen-1-yl>-4-cyanomethyl-2-oxazolidinone
CAS No.:174582-84-4
Molecular Formula:C₁₅H₁₄N₂O₄
Molecular Weight:286.287
Hs Code.:

Synonyms:(4S,5S)-5-<(1R)-1-benzoyloxy-2-propen-1-yl>-4-cyanomethyl-2-oxazolidinone

Suppliers and Price of (4S,5S)-5-<(1R)-1-benzoyloxy-2-propen-1-yl>-4-cyanomethyl-2-oxazolidinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (4S,5S)-5-<(1R)-1-benzoyloxy-2-propen-1-yl>-4-cyanomethyl-2-oxazolidinone

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (4S,5S)-5-<(1R)-1-benzoyloxy-2-propen-1-yl>-4-cyanomethyl-2-oxazolidinone

There total 7 articles about (4S,5S)-5-<(1R)-1-benzoyloxy-2-propen-1-yl>-4-cyanomethyl-2-oxazolidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 143-33-9,25596-52-5
sodium cyanide

: 183298-69-3
(4S,5S)-5-((1R)-1-benzoyloxy-2-propen-1-yl)-4-(p-toluenesulfonyloxy)-methyl-2-oxazolidinone

: 174582-84-4
(4S,5S)-5-<(1R)-1-benzoyloxy-2-propen-1-yl>-4-cyanomethyl-2-oxazolidinone

Guidance literature:: In dimethyl sulfoxide; at 50 ℃; for 0.333333h;
DOI:10.1248/cpb.44.1823

Reference yield:

: 174582-82-2
(4S,5S)-5-<(1R)-1-benzoyloxy-2-propen-1-yl>-4-hydroxymethyloxazolidin-2-one

: 174582-84-4
(4S,5S)-5-<(1R)-1-benzoyloxy-2-propen-1-yl>-4-cyanomethyl-2-oxazolidinone

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / pyridine / CH₂Cl₂ / 22 h / Ambient temperature

2: 99 percent / dimethylsulfoxide / 0.33 h / 50 °C

With pyridine; In dichloromethane; dimethyl sulfoxide;
DOI:10.1248/cpb.44.1823

Reference yield:

: 99679-75-1
Methyl-4,6-O-benzyliden-2-desoxy-2-<(methoxycarbonyl)amino>-α-D-ribo-hexopyranosid-3-ulose

: 174582-84-4
(4S,5S)-5-<(1R)-1-benzoyloxy-2-propen-1-yl>-4-cyanomethyl-2-oxazolidinone

Guidance literature:: Multi-step reaction with 5 steps

1: 90 percent / NaBH₄ / CHCl₃; ethanol / 0.33 h / 0 °C

2: 1.) NaOMe; 2.) NBS, BaCO₃ / 1.) MeOH, reflux, 2 h; 2.) CCl₄, reflux, 1 h

3: Zn / ethanol; H₂O / 3.5 h / Heating

4: NaBH₄ / ethanol / 0.33 h / 0 °C

5: 1.) TsCl / 1.) pyridine, r.t., 22 h; 2.) DMSO, 50 degC, 20 h

With sodium tetrahydroborate; N-Bromosuccinimide; sodium methylate; p-toluenesulfonyl chloride; barium carbonate; zinc; In ethanol; chloroform; water;
DOI:10.3987/com-95-7288