5-(2-amino-4-methoxycarbonylphenyl)-1-isobutyl-1H-imidazole-4-carbonitriIe

Base Information

Chemical Name:5-(2-amino-4-methoxycarbonylphenyl)-1-isobutyl-1H-imidazole-4-carbonitriIe
CAS No.:1426395-91-6
Molecular Formula:C₁₆H₁₈N₄O₂
Molecular Weight:298.345
Hs Code.:

Synonyms:5-(2-amino-4-methoxycarbonylphenyl)-1-isobutyl-1H-imidazole-4-carbonitriIe

Suppliers and Price of 5-(2-amino-4-methoxycarbonylphenyl)-1-isobutyl-1H-imidazole-4-carbonitriIe

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-(2-amino-4-methoxycarbonylphenyl)-1-isobutyl-1H-imidazole-4-carbonitriIe

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Technology Process of 5-(2-amino-4-methoxycarbonylphenyl)-1-isobutyl-1H-imidazole-4-carbonitriIe

There total 2 articles about 5-(2-amino-4-methoxycarbonylphenyl)-1-isobutyl-1H-imidazole-4-carbonitriIe which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 380430-55-7
(2-amino-4-(methoxycarbonyl)phenyl)boronic acid hydrochloride salt

: 960254-00-6
5-iodo-1-isobutyl-1H-imidazole-4-carbonitrile

: 1426395-91-6
5-(2-amino-4-methoxycarbonylphenyl)-1-isobutyl-1H-imidazole-4-carbonitriIe

Guidance literature:: With palladium diacetate; sodium carbonate; triphenylphosphine; In 1,2-dimethoxyethane; water; at 100 ℃; for 3h;

Reference yield:

: 960253-98-9
5-amino-1-isobutyl-1H-imidazole-4-carbonitrile

: 1426395-91-6
5-(2-amino-4-methoxycarbonylphenyl)-1-isobutyl-1H-imidazole-4-carbonitriIe

Guidance literature:: Multi-step reaction with 2 steps

1: diiodomethane; isopentyl nitrite / chloroform / 80 °C

2: palladium diacetate; triphenylphosphine; sodium carbonate / 1,2-dimethoxyethane; water / 3 h / 100 °C

With diiodomethane; palladium diacetate; sodium carbonate; triphenylphosphine; isopentyl nitrite; In 1,2-dimethoxyethane; chloroform; water;