methyl 5-O-(2-O-benzyl-5-O-t-butyldiphenylsilyl-3-O-(2-O-benzoyl-3,5-di-O-benzyl-α-D-arabinofuranosyl)-α-D-arabinofuranosyl)-2,3-di-O-benzyl-α-D-arabinofuranoside

Base Information

Chemical Name:methyl 5-O-(2-O-benzyl-5-O-t-butyldiphenylsilyl-3-O-(2-O-benzoyl-3,5-di-O-benzyl-α-D-arabinofuranosyl)-α-D-arabinofuranosyl)-2,3-di-O-benzyl-α-D-arabinofuranoside
CAS No.:402759-05-1
Molecular Formula:C₇₄H₈₀O₁₄Si
Molecular Weight:1221.53
Hs Code.:

methyl 5-O-(2-O-benzyl-5-O-t-butyldiphenylsilyl-3-O-(2-O-benzoyl-3,5-di-O-benzyl-α-D-arabinofuranosyl)-α-D-arabinofuranosyl)-2,3-di-O-benzyl-α-D-arabinofuranoside

Synonyms:methyl 5-O-(2-O-benzyl-5-O-t-butyldiphenylsilyl-3-O-(2-O-benzoyl-3,5-di-O-benzyl-α-D-arabinofuranosyl)-α-D-arabinofuranosyl)-2,3-di-O-benzyl-α-D-arabinofuranoside

Suppliers and Price of methyl 5-O-(2-O-benzyl-5-O-t-butyldiphenylsilyl-3-O-(2-O-benzoyl-3,5-di-O-benzyl-α-D-arabinofuranosyl)-α-D-arabinofuranosyl)-2,3-di-O-benzyl-α-D-arabinofuranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 5-O-(2-O-benzyl-5-O-t-butyldiphenylsilyl-3-O-(2-O-benzoyl-3,5-di-O-benzyl-α-D-arabinofuranosyl)-α-D-arabinofuranosyl)-2,3-di-O-benzyl-α-D-arabinofuranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 5-O-(2-O-benzyl-5-O-t-butyldiphenylsilyl-3-O-(2-O-benzoyl-3,5-di-O-benzyl-α-D-arabinofuranosyl)-α-D-arabinofuranosyl)-2,3-di-O-benzyl-α-D-arabinofuranoside

There total 10 articles about methyl 5-O-(2-O-benzyl-5-O-t-butyldiphenylsilyl-3-O-(2-O-benzoyl-3,5-di-O-benzyl-α-D-arabinofuranosyl)-α-D-arabinofuranosyl)-2,3-di-O-benzyl-α-D-arabinofuranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 402758-78-5
p-cresyl 2-O-benzoyl-3,5-di-O-benzyl-1-thio-α-D-arabinofuranoside

: 402759-04-0
methyl 5-O-(2-O-benzyl-5-O-tert-butyldiphenylsilyl-α-D-arabinofuranosyl)-2,3-di-O-benzyl-α-D-arabinofuranoside

: 402759-05-1
methyl 5-O-(2-O-benzyl-5-O-t-butyldiphenylsilyl-3-O-(2-O-benzoyl-3,5-di-O-benzyl-α-D-arabinofuranosyl)-α-D-arabinofuranosyl)-2,3-di-O-benzyl-α-D-arabinofuranoside

Guidance literature:: With N-iodo-succinimide; molecular sieve; silver trifluoromethanesulfonate; In dichloromethane; at 0 ℃;
DOI:10.1021/jo010910e

Reference yield:

: 16896-03-0,16896-04-1,30589-89-0,53496-31-4,70831-62-8,103476-40-0,128821-26-1
methyl 2,3-di-O-benzyl-α-D-arabinofuranoside

: 402759-05-1
methyl 5-O-(2-O-benzyl-5-O-t-butyldiphenylsilyl-3-O-(2-O-benzoyl-3,5-di-O-benzyl-α-D-arabinofuranosyl)-α-D-arabinofuranosyl)-2,3-di-O-benzyl-α-D-arabinofuranoside

Guidance literature:: Multi-step reaction with 7 steps

1: 84 percent / molecular sieves; NIS; AgOTf / CH₂Cl₂ / 0 °C

2: 95 percent / NaOCH₃ / methanol / 2 h / 20 °C

3: 68 percent / pyridine / 8 h / 20 °C

4: NaH / dimethylformamide / 2 h / 0 °C

5: 770 mg / n-Bu₄NF / tetrahydrofuran / 20 °C

6: 68 percent / pyridine / 36 h / 20 °C

7: 75 percent / molecular sieves; NIS; AgOTf / CH₂Cl₂ / 0 °C

With N-iodo-succinimide; molecular sieve; tetrabutyl ammonium fluoride; sodium methylate; silver trifluoromethanesulfonate; sodium hydride; In tetrahydrofuran; pyridine; methanol; dichloromethane; N,N-dimethyl-formamide; 2: Zemplen deacylation;
DOI:10.1021/jo010910e

Reference yield:

: 329360-22-7
1-O-methyl-3,5-di-O-benzyl-α-D-arabinofuranose

: 402759-05-1
methyl 5-O-(2-O-benzyl-5-O-t-butyldiphenylsilyl-3-O-(2-O-benzoyl-3,5-di-O-benzyl-α-D-arabinofuranosyl)-α-D-arabinofuranosyl)-2,3-di-O-benzyl-α-D-arabinofuranoside

Guidance literature:: Multi-step reaction with 3 steps

1: 90 percent / pyridine / 2 h / 20 °C

2: 72 percent / BF₃*OEt₂ / CH₂Cl₂ / 2 h / 0 °C

3: 75 percent / molecular sieves; NIS; AgOTf / CH₂Cl₂ / 0 °C

With N-iodo-succinimide; molecular sieve; boron trifluoride diethyl etherate; silver trifluoromethanesulfonate; In pyridine; dichloromethane;
DOI:10.1021/jo010910e