Ethyl 2-(4-methoxybenzyl)-3-oxobutyrate

Base Information

Chemical Name:Ethyl 2-(4-methoxybenzyl)-3-oxobutyrate
CAS No.:36600-75-6
Molecular Formula:C₁₄H₁₈O₄
Molecular Weight:250.295
Hs Code.:
DSSTox Substance ID:DTXSID001270707
Nikkaji Number:J259.134K

Synonyms:ethyl 2-(4-methoxybenzyl)-3-oxobutyrate;36600-75-6;SCHEMBL854302;YQKWREJHOWIMQE-UHFFFAOYSA-N;DTXSID001270707;Ethyl2-(4-methoxybenzyl)-3-oxobutyrate;ethyl 2-(4-methoxybenzyl)-3-oxobutanoate;Ethyl alpha-acetyl-4-methoxybenzenepropanoate;alpha-(4-methoxybenzyl)-acetoacetic acid ethyl ester;2-(4-Methoxy-benzyl)-3-oxo-butyric acid ethyl ester

Suppliers and Price of Ethyl 2-(4-methoxybenzyl)-3-oxobutyrate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Ethyl 2-(4-methoxybenzyl)-3-oxobutyrate

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:250.12050905
Heavy Atom Count:18
Complexity:280

Purity/Quality:: 99% ，98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)C(CC1=CC=C(C=C1)OC)C(=O)C

Technology Process of Ethyl 2-(4-methoxybenzyl)-3-oxobutyrate

There total 15 articles about Ethyl 2-(4-methoxybenzyl)-3-oxobutyrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 104-21-2
p-methoxybenzyl acetate

: 141-97-9
ethyl acetoacetate

: 36600-75-6
2-(4-methoxy-benzyl)-3-oxo-butyric acid ethyl ester

Guidance literature:: With proton-exchanged montmorillonite;
DOI:10.1016/j.tet.2014.01.064

Reference yield: 82.0%

: 141-97-9
ethyl acetoacetate

: 36600-75-6
2-(4-methoxy-benzyl)-3-oxo-butyric acid ethyl ester

Guidance literature:: ethyl acetoacetate; With sodium hydride; In tetrahydrofuran; at 0 ℃; for 0.166667h; Inert atmosphere;

4-methoxybenzyl halide; In tetrahydrofuran; at 20 ℃; for 1h; Inert atmosphere;
DOI:10.1002/anie.201904899

Reference yield: 79.0%

: 141-97-9
ethyl acetoacetate

: 824-94-2
p-methoxybenzyl chloride

: 36600-75-6
2-(4-methoxy-benzyl)-3-oxo-butyric acid ethyl ester

Guidance literature:: ethyl acetoacetate; With potassium tert-butylate; In tert-butyl alcohol; at 20 ℃; for 0.666667h;

p-methoxybenzyl chloride; In tert-butyl alcohol; at 50 ℃;