2-(4-methoxy-benzyl)-3-oxo-butyric acid ethyl ester

Base Information Edit

Chemical Name:2-(4-methoxy-benzyl)-3-oxo-butyric acid ethyl ester
CAS No.:36600-75-6
Molecular Formula:C₁₄H₁₈O₄
Molecular Weight:250.295
Hs Code.:
Mol file:36600-75-6.mol

Synonyms:2-(4-methoxy-benzyl)-3-oxo-butyric acid ethyl ester

Suppliers and Price of 2-(4-methoxy-benzyl)-3-oxo-butyric acid ethyl ester

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 2 raw suppliers

Chemical Property of 2-(4-methoxy-benzyl)-3-oxo-butyric acid ethyl ester Edit

Chemical Property:

Purity/Quality:: 99% ，98% ^*data from raw suppliers

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Technology Process of 2-(4-methoxy-benzyl)-3-oxo-butyric acid ethyl ester

There total 15 articles about 2-(4-methoxy-benzyl)-3-oxo-butyric acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 104-21-2
p-methoxybenzyl acetate

: 141-97-9
ethyl acetoacetate

: 36600-75-6
2-(4-methoxy-benzyl)-3-oxo-butyric acid ethyl ester

Guidance literature:: With proton-exchanged montmorillonite;
DOI:10.1016/j.tet.2014.01.064

Reference yield: 82.0%

: 141-97-9
ethyl acetoacetate

: 36600-75-6
2-(4-methoxy-benzyl)-3-oxo-butyric acid ethyl ester

Guidance literature:: ethyl acetoacetate; With sodium hydride; In tetrahydrofuran; at 0 ℃; for 0.166667h; Inert atmosphere;

4-methoxybenzyl halide; In tetrahydrofuran; at 20 ℃; for 1h; Inert atmosphere;
DOI:10.1002/anie.201904899

Reference yield: 79.0%

: 141-97-9
ethyl acetoacetate

: 824-94-2
p-methoxybenzyl chloride

: 36600-75-6
2-(4-methoxy-benzyl)-3-oxo-butyric acid ethyl ester

Guidance literature:: ethyl acetoacetate; With potassium tert-butylate; In tert-butyl alcohol; at 20 ℃; for 0.666667h;

p-methoxybenzyl chloride; In tert-butyl alcohol; at 50 ℃;