2-(4-Chlorophenyl)-8-methylimidazo[1,2-a]pyridine

Base Information

Chemical Name:2-(4-Chlorophenyl)-8-methylimidazo[1,2-a]pyridine
CAS No.:442554-03-2
Molecular Formula:C₁₄H₁₁ClN₂
Molecular Weight:242.708
Hs Code.:
DSSTox Substance ID:DTXSID101324070
ChEMBL ID:CHEMBL1379976
Mol file:442554-03-2.mol

Synonyms:2-(4-chlorophenyl)-8-methylimidazo[1,2-a]pyridine;442554-03-2;Oprea1_229640;MLS000721124;CHEMBL1379976;DTXSID101324070;HMS2686E12;BBL020371;MFCD00444769;STK891981;AKOS001476805;SMR000335316;CS-0192285;EU-0078235;3P-060;E89451;EN300-1221154;AG-996/31204057;SR-01000492565;SR-01000492565-1;F0919-2130

Suppliers and Price of 2-(4-Chlorophenyl)-8-methylimidazo[1,2-a]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AOBChem
2-(4-Chlorophenyl)-8-methylimidazo[1,2-a]pyridine 97%
5g
$ 1235.00

American Custom Chemicals Corporation
2-(4-CHLOROPHENYL)-8-METHYLIMIDAZO[1,2-A]PYRIDINE 95.00%
5MG
$ 623.82

American Custom Chemicals Corporation
2-(4-CHLOROPHENYL)-8-METHYLIMIDAZO[1,2-A]PYRIDINE 95.00%
10MG
$ 618.50

American Custom Chemicals Corporation
2-(4-CHLOROPHENYL)-8-METHYLIMIDAZO[1,2-A]PYRIDINE 95.00%
1MG
$ 586.97

aablocks
2-(4-Chlorophenyl)-8-methylimidazo[1,2-a]pyridine
250mg
$ 199.00

Total 1 raw suppliers

Chemical Property of 2-(4-Chlorophenyl)-8-methylimidazo[1,2-a]pyridine

Chemical Property:

XLogP3:4.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:242.0610761
Heavy Atom Count:17
Complexity:263

Purity/Quality:: 2-(4-Chlorophenyl)-8-methylimidazo[1,2-a]pyridine 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=CN2C1=NC(=C2)C3=CC=C(C=C3)Cl

Technology Process of 2-(4-Chlorophenyl)-8-methylimidazo[1,2-a]pyridine

There total 3 articles about 2-(4-Chlorophenyl)-8-methylimidazo[1,2-a]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 1603-40-3
3-methylpyridin-2-ylamine

: 536-38-9
4-chlorobenzoylmethyl bromide

: 442554-03-2
2-(4-chlorophenyl)-8-methylimidazo[1,2-a]pyridine

Guidance literature:: In water; isopropyl alcohol; at 75 ℃; Microwave irradiation; Green chemistry;
DOI:10.1021/acscombsci.7b00173

Reference yield: 76.0%

: 1603-40-3
3-methylpyridin-2-ylamine

: 75230-50-1
p-chloroacetophenone tosylhydrazone

: 442554-03-2
2-(4-chlorophenyl)-8-methylimidazo[1,2-a]pyridine

Guidance literature:: With trifluoromethanesulfonyloxy(triphenylphosphine)gold(I); oxygen; cesium acetate; In toluene; at 110 ℃; for 12h;
DOI:10.1016/j.catcom.2016.10.033

Reference yield:

: 99-91-2
para-chloroacetophenone

: 442554-03-2
2-(4-chlorophenyl)-8-methylimidazo[1,2-a]pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: tetra-N-butylammonium tribromide / tert-Amyl alcohol / 20 °C

2: tert-Amyl alcohol / 2 h / 80 °C

With tetra-N-butylammonium tribromide; In tert-Amyl alcohol;
DOI:10.1002/ejoc.201800578