(3R,4R)-3,4-DIHYDROXYCYCLOHEXA-1,5-DIENE-1-CARBOXYLIC ACID

Base Information

• Chemical Name: (3R,4R)-3,4-DIHYDROXYCYCLOHEXA-1,5-DIENE-1-CARBOXYLIC ACID
• CAS No.: 108646-25-9
• Molecular Formula: C7H8 O4
• Molecular Weight: 156.138
• Hs Code.: 2918199090
• Mol file: 108646-25-9.mol

Synonyms:1,5-Cyclohexadiene-1-carboxylicacid, 3,4-dihydroxy-, (3R-trans)-

Chemical Property of (3R,4R)-3,4-DIHYDROXYCYCLOHEXA-1,5-DIENE-1-CARBOXYLIC ACID

Chemical Property:

• PSA: 77.76000
• LogP: -0.71100

Purity/Quality:

99% ^*data from raw suppliers

(3R,4R)-3,4-Dihydroxycyclohexa-1,5-diene-1-carboxylic acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (3R,4R)-3,4-DIHYDROXYCYCLOHEXA-1,5-DIENE-1-CARBOXYLIC ACID

There total 4 articles about (3R,4R)-3,4-DIHYDROXYCYCLOHEXA-1,5-DIENE-1-CARBOXYLIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

chorismic acid (617-12-9) → (3R,4R)-3,4-dihydroxycyclohexa-1,5-diene carboxylic acid (108646-25-9) + 2-oxo-propionic acid (127-17-3)

Guidance literature:

With FkbO from Streptomyces hygroscopicus subsp. ascomyceticus chorismatases; for 20h; Enzymatic reaction;

DOI:10.1021/jacs.5b05559

Reference yield:

chorismic acid (617-12-9) → 2-18O-pyruvic acid + (3R,4R)-3,4-dihydroxycyclohexa-1,5-diene carboxylic acid (108646-25-9)

Guidance literature:

With FkbO from Streptomyces hygroscopicus subsp. ascomyceticus chorismatases; ¹⁸O-labeled water; In aq. buffer; at 20 ℃; for 2h; Enzymatic reaction;

DOI:10.1021/jacs.5b05559

Reference yield:

→ trans-3,4-Dihydroxy-3,4-dihydrobenzoesaeure (6666-91-7,24554-00-5,65825-58-3,108646-25-9)

Guidance literature:

Dihydroxyester 9, KOH;

DOI:10.1021/ja00816a039

upstream raw materials:

chorismic acid

Downstream raw materials:

3-Carboxyphenol

C₂₀H₃₇BrO₄Si₂

C₂₀H₃₈O₅Si₂

C₂₀H₃₈O₄Si₂