Technology Process of 2-(3,4-dimethoxybenzyl)-3-phenylpropionyl chloride
There total 6 articles about 2-(3,4-dimethoxybenzyl)-3-phenylpropionyl chloride which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 99 percent / hydrogen / 10percent Pd/C / methanol; dioxane / 6 h / 2844.3 Torr
2: 1.) NaOCH3 / 1.) methanol, 30 min, 2.) DMF, diethyl ether, 2 h
3: 2 N NaOH / H2O; methanol / 2 h / Heating
4: 6 N HCl / H2O / 2 h / Heating
5: oxalyl chloride, DMF / various solvent(s) / 1 h
With
hydrogenchloride; sodium hydroxide; oxalyl dichloride; hydrogen; sodium methylate; N,N-dimethyl-formamide;
palladium on activated charcoal;
In
1,4-dioxane; methanol; water;
DOI:10.1021/ja00529a031
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 92 percent / 3,4-dimethoxybenzoic acid, piperidine / 1 h / 85 - 90 °C
2: 99 percent / hydrogen / 10percent Pd/C / methanol; dioxane / 6 h / 2844.3 Torr
3: 1.) NaOCH3 / 1.) methanol, 30 min, 2.) DMF, diethyl ether, 2 h
4: 2 N NaOH / H2O; methanol / 2 h / Heating
5: 6 N HCl / H2O / 2 h / Heating
6: oxalyl chloride, DMF / various solvent(s) / 1 h
With
piperidine; hydrogenchloride; sodium hydroxide; oxalyl dichloride; hydrogen; sodium methylate; Veratric acid; N,N-dimethyl-formamide;
palladium on activated charcoal;
In
1,4-dioxane; methanol; water;
DOI:10.1021/ja00529a031
- Guidance literature:
-
With
oxalyl dichloride; N,N-dimethyl-formamide;
In
various solvent(s);
for 1h;
DOI:10.1021/ja00529a031
