N-diphenylphosphanyl-1-[2-(diphenylphosphanylamino)-5,6,7,8-tetrahydronaphthalen-1-yl]-5,6,7,8-tetrahydronaphthalen-2-amine

Base Information

• Chemical Name: N-diphenylphosphanyl-1-[2-(diphenylphosphanylamino)-5,6,7,8-tetrahydronaphthalen-1-yl]-5,6,7,8-tetrahydronaphthalen-2-amine
• CAS No.: 229177-79-1
• Molecular Formula: C₄₄H₄₂N₂P₂
• Molecular Weight: 660.778
• DSSTox Substance ID: DTXSID90448659
• Nikkaji Number: J1.687.206G
• Wikidata: Q82267746
• Mol file: 229177-79-1.mol

Synonyms:229177-79-1;208248-67-3;N-diphenylphosphanyl-1-[2-(diphenylphosphanylamino)-5,6,7,8-tetrahydronaphthalen-1-yl]-5,6,7,8-tetrahydronaphthalen-2-amine;(R)-(+)-2,2'-BIS(N-DIPHENYLPHOSPHINOAMINO)-5,5',6,6',7,7',8,8'-OCTAHYDRO-1,1'-BINAPHTHYL;(S)-(-)-2,2'-Bis(N-diphenylphosphinoamino)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl, CTH-(S)-BINAM;(S)-(-)-2,2'-Bis(N-diphenylphosphinoamino)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl;N,N'-[(1R)-5,5',6,6',7,7',8,8'-Octahydro[1,1'-binaphthalene]-2,2'-diyl]bis[P,P-diphenylphosphinous amide];(S)-2,2'-Bis(N-diphenylphosphinoamino)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl;(R)-N2,N2'-Bis(diphenylphosphanyl)-5,5',6,6',7,7',8,8'-octahydro-[1,1'-binaphthalene]-2,2'-diamine;Phosphinous amide, N,N'-[(1S)-5,5',6,6',7,7',8,8'-octahydro[1,1'-binaphthalene]-2,2'-diyl]bis[P,P-diphenyl- (9CI);Phosphinous amide,N,N'-[(1R)-5,5',6,6',7,7',8,8'-octahydro[1,1'-binaphthalene]-2,2'-diyl]bis[P,P-diphenyl-;SCHEMBL1039359;DTXSID90448659;MFCD04974231;AKOS025294948;AS-75000;PHOSPHINOUS AMIDE,N,N'-[(1S)-5,5',6,6',7,7',8,8'-OCTAHYDRO[1,1'-BINAPHTHALENE]-2,2'-DIYL]BIS[P,P-DIPHENYL-(9CI);CS-0086888;CS-0090871;CS-0202919;5,5'-Bi[6-(diphenylphosphinoamino)tetralin];S-(-)-2,2'-Bis(N-diphenylphosphinoamino)-5,5'6,6'7,7',8,8'-octahydro-1,1'-binaphthyl;N-{2'-[(DIPHENYLPHOSPHANYL)AMINO]-5H,5'H,6H,6'H,7H,7'H,8H,8'H-[1,1'-BINAPHTHALEN]-2-YL}-1,1-DIPHENYLPHOSPHANAMINE

Chemical Property of N-diphenylphosphanyl-1-[2-(diphenylphosphanylamino)-5,6,7,8-tetrahydronaphthalen-1-yl]-5,6,7,8-tetrahydronaphthalen-2-amine

Chemical Property:

• Boiling Point: 787.1°Cat760mmHg
• Flash Point: 429.8°C
• PSA: 51.24000
• Density: g/cm³
• LogP: 10.17680
• XLogP3: 12.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 9
• Exact Mass: 660.28232334
• Heavy Atom Count: 48
• Complexity: 838

Purity/Quality:

99% ^*data from raw suppliers

(S)-(-)-2,2'-BIS(N-DIPHENYLPHOSPHINOAMINO)-5,5',6,6',7,7',8,8'-OCTAHYDRO-1,1'-BINAPHTHYL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCC2=C(C1)C=CC(=C2C3=C(C=CC4=C3CCCC4)NP(C5=CC=CC=C5)C6=CC=CC=C6)NP(C7=CC=CC=C7)C8=CC=CC=C8

Technology Process of N-diphenylphosphanyl-1-[2-(diphenylphosphanylamino)-5,6,7,8-tetrahydronaphthalen-1-yl]-5,6,7,8-tetrahydronaphthalen-2-amine

There total 3 articles about N-diphenylphosphanyl-1-[2-(diphenylphosphanylamino)-5,6,7,8-tetrahydronaphthalen-1-yl]-5,6,7,8-tetrahydronaphthalen-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

chloro-diphenylphosphine (1079-66-9,74391-44-9) + (R)-5,6,7,8,5',6',7',8'-octahydro-[1,1']binaphthalenyl-2,2'-diamine → (Ra)-N,N'-bis(diphenylphosphanyl)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl-2,2'-diamine (229177-79-1)

Guidance literature:

With triethylamine; In dichloromethane; for 24h; Heating;

DOI:10.1016/S0957-4166(01)00399-8

Reference yield:

1,1'-binaphthalene-2,2'-diamine (4488-22-6,18531-95-8) → (R)-2,2'-bis(diphenylphosphinoamino)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl (229177-79-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 88 percent / H₂ / PtO₂ / aq. acetic acid / 24 h / 50 °C / 2280 Torr

2: 1.) n-BuLi / 1.) THF, hexane, -30 deg C, 2 h, 2.) THF, hexane, 5 h

With n-butyllithium; hydrogen; platinum(IV) oxide; In acetic acid;

DOI:10.1021/ja974045k

Reference yield:

chloro-diphenylphosphine (1079-66-9,74391-44-9) + 5,6,7,8,5',6',7',8'-octahydro-[1,1']binaphthalenyl-2,2'-diamine (208248-66-2,229177-78-0) → (R)-2,2'-bis(diphenylphosphinoamino)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl (229177-79-1)

Guidance literature:

With n-butyllithium; Yield given. Multistep reaction; 1.) THF, hexane, -30 deg C, 2 h, 2.) THF, hexane, 5 h;

DOI:10.1021/ja974045k

upstream raw materials:

chloro-diphenylphosphine

5,6,7,8,5',6',7',8'-octahydro-[1,1']binaphthalenyl-2,2'-diamine

1,1'-binaphthalene-2,2'-diamine