N-(tert-butoxycarbonyl)-L-tyrosine (2'S,3'R)-2'-acetoxy-tetrahydrofuran-3'-yl ester

Base Information

Chemical Name:N-(tert-butoxycarbonyl)-L-tyrosine (2'S,3'R)-2'-acetoxy-tetrahydrofuran-3'-yl ester
CAS No.:1262029-80-0
Molecular Formula:C₂₀H₂₇NO₈
Molecular Weight:409.436
Hs Code.:

Synonyms:N-(tert-butoxycarbonyl)-L-tyrosine (2'S,3'R)-2'-acetoxy-tetrahydrofuran-3'-yl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(tert-butoxycarbonyl)-L-tyrosine (2'S,3'R)-2'-acetoxy-tetrahydrofuran-3'-yl ester

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Technology Process of N-(tert-butoxycarbonyl)-L-tyrosine (2'S,3'R)-2'-acetoxy-tetrahydrofuran-3'-yl ester

There total 1 articles about N-(tert-butoxycarbonyl)-L-tyrosine (2'S,3'R)-2'-acetoxy-tetrahydrofuran-3'-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 27.0%

: 108-05-4,9003-20-7
vinyl acetate

: 1262029-74-2
N-(tert-butoxycarbonyl)-L-tyrosine 2'-hydroxy-tetrahydrofuran-3'-yl ester

: 1262029-80-0
N-(tert-butoxycarbonyl)-L-tyrosine (2'S,3'R)-2'-acetoxy-tetrahydrofuran-3'-yl ester

Guidance literature:: With Candida antarctica lipase B; In chloroform; at 20 ℃; for 182h; optical yield given as %de; diastereoselective reaction; Enzymatic reaction;
DOI:10.1016/j.molcatb.2010.09.008

Reference yield: 80.0%

: 1262029-80-0
N-(tert-butoxycarbonyl)-L-tyrosine (2'S,3'R)-2'-acetoxy-tetrahydrofuran-3'-yl ester

: 1262029-87-7
N-(tert-butoxycarbonyl)-L-tyrosine (3'R)-2'-hydroxy-tetrahydropyran-3'-yl ester

Guidance literature:: With Candida antarctica lipase B; In water; acetonitrile; at 20 ℃; for 216h; regioselective reaction; Enzymatic reaction;
DOI:10.1016/j.molcatb.2010.09.008