6-(methyl 2,3,4-tri-O-benzyl-6-deoxy-α-D-manno-pyranozide) boronic acid

Base Information

Chemical Name:6-(methyl 2,3,4-tri-O-benzyl-6-deoxy-α-D-manno-pyranozide) boronic acid
CAS No.:1304043-35-3
Molecular Formula:C₂₉H₃₅BO₇
Molecular Weight:506.404
Hs Code.:

Synonyms:6-(methyl 2,3,4-tri-O-benzyl-6-deoxy-α-D-manno-pyranozide) boronic acid

Suppliers and Price of 6-(methyl 2,3,4-tri-O-benzyl-6-deoxy-α-D-manno-pyranozide) boronic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 6-(methyl 2,3,4-tri-O-benzyl-6-deoxy-α-D-manno-pyranozide) boronic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 6-(methyl 2,3,4-tri-O-benzyl-6-deoxy-α-D-manno-pyranozide) boronic acid

There total 6 articles about 6-(methyl 2,3,4-tri-O-benzyl-6-deoxy-α-D-manno-pyranozide) boronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 617-86-7
triethylsilane

: 10294-33-4
boron tribromide

: 122588-56-1
(2S,3S,4S,5R,6R)-3,4,5-Tris-benzyloxy-2-methoxy-6-vinyl-tetrahydro-pyran

: 1310-73-2
sodium hydroxide

: 1304043-35-3
6-(methyl 2,3,4-tri-O-benzyl-6-deoxy-α-D-manno-pyranozide) boronic acid

Guidance literature:: triethylsilane; boron tribromide; (2S,3S,4S,5R,6R)-3,4,5-Tris-benzyloxy-2-methoxy-6-vinyl-tetrahydro-pyran; In pentane; at -78 - 20 ℃; for 3.25h; Inert atmosphere;

sodium hydroxide; In pentane; at 20 ℃; for 0.5h;

Reference yield:

: 34212-64-1,641635-63-4
methyl 2,3,4-tri-O-benzyl-α-D-mannopyranoside

: 1304043-35-3
6-(methyl 2,3,4-tri-O-benzyl-6-deoxy-α-D-manno-pyranozide) boronic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: pyridinium chlorochromate / dichloromethane / 1 h / 20 °C / Molecular sieve

2.1: n-butyllithium / tetrahydrofuran / 0.5 h / 15 °C / Inert atmosphere

2.2: 18 h / -78 - 20 °C

3.1: pentane / 3.25 h / -78 - 20 °C / Inert atmosphere

3.2: 0.5 h / 20 °C

With n-butyllithium; pyridinium chlorochromate; In tetrahydrofuran; dichloromethane; pentane;

Reference yield:

: 617-04-9
(2R,3S,4S,5S,6S)-2-(hydroxymethyl)-6-methoxytetrahydro-2H-pyran-3,4,5-triol

: 1304043-35-3
6-(methyl 2,3,4-tri-O-benzyl-6-deoxy-α-D-manno-pyranozide) boronic acid

Guidance literature:: Multi-step reaction with 6 steps

1.1: dmap; pyridine / 1.5 h

2.1: potassium hydroxide / 1 h / 80 °C

3.1: water; ammonium cerium (IV) nitrate / acetonitrile / 60 °C

4.1: pyridinium chlorochromate / dichloromethane / 1 h / 20 °C / Molecular sieve

5.1: n-butyllithium / tetrahydrofuran / 0.5 h / 15 °C / Inert atmosphere

5.2: 18 h / -78 - 20 °C

6.1: pentane / 3.25 h / -78 - 20 °C / Inert atmosphere

6.2: 0.5 h / 20 °C

With pyridine; dmap; n-butyllithium; ammonium cerium (IV) nitrate; water; pyridinium chlorochromate; potassium hydroxide; In tetrahydrofuran; dichloromethane; acetonitrile; pentane;