N-ethylguanidine hydrochloride

Base Information

• Chemical Name: N-ethylguanidine hydrochloride
• CAS No.: 19341-54-9
• Molecular Formula: C3H9N3^.HCl
• Molecular Weight: 123.586
• Hs Code.: 2925290090
• European Community (EC) Number: 242-974-1
• DSSTox Substance ID: DTXSID40941024
• Mol file: 19341-54-9.mol

Synonyms:N-ethylguanidine;N-ethylguanidine hydrochloride;N-ethylguanidine sulfate (1:1);N-ethylguanidine sulfate (2:1)

Chemical Property of N-ethylguanidine hydrochloride

Chemical Property:

• Vapor Pressure: 5.22E-23mmHg at 25°C
• Melting Point: 115-118 °C
• Boiling Point: 186.2 °C at 760 mmHg
• Flash Point: 66.4 °C
• PSA: 61.90000
• LogP: 1.48230
• Sensitive.: Hygroscopic
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 123.0563250
• Heavy Atom Count: 7
• Complexity: 53.1

Purity/Quality:

97% ^*data from raw suppliers

N-Ethylguanidinehydrochloride ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCN=C(N)N.Cl

Technology Process of N-ethylguanidine hydrochloride

There total 1 articles about N-ethylguanidine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 1-ethylguanidine hydrochloride (19341-54-9)

Guidance literature:

Reference yield: 86.0%

1-ethylguanidine hydrochloride (19341-54-9) + 1-Acetyl-3-[1-(4-fluoro-phenyl)-1-pyrrolidin-1-yl-meth-(Z)-ylidene]-piperidin-4-one (1027568-90-6) → 6-acetyl-4-(4-fluorophenyl)-2-ethylamino-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine (144507-11-9)

Guidance literature:

With sodium ethanolate; In ethanol; for 3h; Heating;

DOI:10.1016/0223-5234(92)90085-F

Reference yield: 70.0%

2-dimethylaminomethylene-1,3-bis(dimethylimonio)propane diperchlorate (2009-81-6) + 1-ethylguanidine hydrochloride (19341-54-9) → 2-Ethylaminopyrimidine-5-carboxaldehyde (137279-29-9)

Guidance literature:

With ethanol; sodium hydride; In ethanol; Heating;

Downstream raw materials:

Ethyl-(4-phenyl-5,6-dihydro-benzo[h]quinazolin-2-yl)-amine

2-Ethylaminopyrimidine-5-carboxaldehyde

6-acetyl-4-(4-fluorophenyl)-2-ethylamino-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine

1-(2-Ethylaminopyrimidin-4-yl)ethanone