(1E,3Z)-6-benzyloxy-1-(4-methoxyphenyl)-4-methylhexa-1,3-diene

Base Information

• Chemical Name: (1E,3Z)-6-benzyloxy-1-(4-methoxyphenyl)-4-methylhexa-1,3-diene
• CAS No.: 1118759-66-2
• Molecular Formula: C₂₁H₂₄O₂
• Molecular Weight: 308.42
• Mol file: 1118759-66-2.mol

Synonyms:(1E,3Z)-6-benzyloxy-1-(4-methoxyphenyl)-4-methylhexa-1,3-diene

Chemical Property of (1E,3Z)-6-benzyloxy-1-(4-methoxyphenyl)-4-methylhexa-1,3-diene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of (1E,3Z)-6-benzyloxy-1-(4-methoxyphenyl)-4-methylhexa-1,3-diene

There total 4 articles about (1E,3Z)-6-benzyloxy-1-(4-methoxyphenyl)-4-methylhexa-1,3-diene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2E,4E)-2-(2-benzyloxyethyl)-5-(4-methoxyphenyl)penta-2,4-dien-1-ol (1118759-63-9) → (1E,3Z)-6-benzyloxy-1-(4-methoxyphenyl)-4-methylhexa-1,3-diene (1118759-66-2)

Guidance literature:

(2E,4E)-2-(2-benzyloxyethyl)-5-(4-methoxyphenyl)penta-2,4-dien-1-ol; With sulfur trioxide pyridine complex; In tetrahydrofuran; at 0 ℃; for 3h;

With lithium aluminium tetrahydride; In tetrahydrofuran; at 20 ℃; for 20h; Further stages.;

DOI:10.1016/j.mencom.2008.03.010

Reference yield:

C28H30O5S → (1E,3Z)-6-benzyloxy-1-(4-methoxyphenyl)-4-methylhexa-1,3-diene (1118759-66-2) + (1E,3E)-6-benzyloxy-1-(4-methoxyphenyl)-4-methylhexa-1,3-diene

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; diethyl ether; hexane; at -15 - 20 ℃; for 20h; optical yield given as %de;

DOI:10.1007/s11172-010-0172-6

Reference yield:

(2E,4E)-2-(2-benzyloxyethyl)-5-(4-methoxyphenyl)penta-2,4-dien-1-ol (1118759-63-9) → (1E,3Z)-6-benzyloxy-1-(4-methoxyphenyl)-4-methylhexa-1,3-diene (1118759-66-2) + C21H24O2 (1257303-44-8) + C21H24O2 (1257303-42-6)

Guidance literature:

(2E,4E)-2-(2-benzyloxyethyl)-5-(4-methoxyphenyl)penta-2,4-dien-1-ol; With pyridine-SO₃ complex; In tetrahydrofuran; at -15 - 0 ℃; for 2.83333h;

With lithium aluminium tetrahydride; In tetrahydrofuran; at -10 - 20 ℃; for 24h;

DOI:10.1007/s11172-010-0172-6

upstream raw materials:

(2E,4E)-2-(2-benzyloxyethyl)-5-(4-methoxyphenyl)penta-2,4-dien-1-ol

(E,E)-2-(2-benzyloxyethyl)-5-(4-methoxyphenyl)penta-2,4-dien-1-al

Downstream raw materials:

(3Z,5E)-6-(4-methoxyphenyl)-3-methylhexa-3,5-dien-1-ol