4-methoxyphenyl 2,4,6-O-tri-O-acetyl-3-O-allyl-β-D-galactopyranoside

Base Information

• Chemical Name: 4-methoxyphenyl 2,4,6-O-tri-O-acetyl-3-O-allyl-β-D-galactopyranoside
• CAS No.: 343254-39-7
• Molecular Formula: C₂₂H₂₈O₁₀
• Molecular Weight: 452.458
• Mol file: 343254-39-7.mol

Synonyms:4-methoxyphenyl 2,4,6-O-tri-O-acetyl-3-O-allyl-β-D-galactopyranoside

Chemical Property of 4-methoxyphenyl 2,4,6-O-tri-O-acetyl-3-O-allyl-β-D-galactopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-methoxyphenyl 2,4,6-O-tri-O-acetyl-3-O-allyl-β-D-galactopyranoside

There total 3 articles about 4-methoxyphenyl 2,4,6-O-tri-O-acetyl-3-O-allyl-β-D-galactopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

acetic anhydride (108-24-7) + p-methoxyphenyl 3-O-allyl-β-D-galactopyranoside (144985-19-3) → 4-methoxyphenyl 2,4,6-O-tri-O-acetyl-3-O-allyl-β-D-galactopyranoside (343254-39-7)

Guidance literature:

With pyridine; at 0 ℃; for 2h;

DOI:10.1080/07328303.2010.508141

Reference yield:

C27H32O9 + acetic anhydride (108-24-7) → 4-methoxyphenyl 2,4,6-O-tri-O-acetyl-3-O-allyl-β-D-galactopyranoside (343254-39-7)

Guidance literature:

With perchloric acid supported over silica; at 20 ℃; for 0.25h; regioselective reaction;

DOI:10.1016/j.carres.2019.107830

Reference yield:

4-methoxyphenyl β-D-galactopyranoside (3150-20-7,6032-32-2,28541-75-5,85481-53-4,89731-58-8,109121-56-4,121468-39-1,12167-34-9) → 4-methoxyphenyl 2,4,6-O-tri-O-acetyl-3-O-allyl-β-D-galactopyranoside (343254-39-7)

Guidance literature:

Multi-step reaction with 2 steps

1.1: di(n-butyl)tin oxide / toluene / 18 h / Reflux

1.2: 2 h / Reflux

2.1: pyridine / 2 h / 0 °C

With pyridine; di(n-butyl)tin oxide; In toluene;

DOI:10.1080/07328303.2010.508141

upstream raw materials:

acetic anhydride

p-methoxyphenyl 3-O-allyl-β-D-galactopyranoside

4-methoxyphenyl β-D-galactopyranoside

Downstream raw materials:

4-methoxyphenyl 2-O-acetyl-3-O-allyl-6-O-tert-butyldiphenylsilyl-β-D-galactopyranoside

4-methoxyphenyl O-(2,4,6-tri-O-acetyl-3-O-allyl-β-D-galactopyranosyl)-(1->4)-β-D-xylopyranoside

4-methoxyphenyl O-(2,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-(1->4)-2,3-di-O-(4-methylbenzoyl)-β-D-xylopyranoside

4-methoxyphenyl O-(2,4,6-tri-O-acetyl-3-O-allyl-β-D-galactopyranosyl)-(1->4)-2,3-di-O-(4-methylbenzoyl)-β-D-xylopyranoside