(2S,4S)-1-acetyl-2-phenylcarbamoyl-4-pyrrolidinyl acetate

Base Information

Chemical Name:(2S,4S)-1-acetyl-2-phenylcarbamoyl-4-pyrrolidinyl acetate
CAS No.:77937-79-2
Molecular Formula:C₁₅H₁₈N₂O₄
Molecular Weight:290.319
Hs Code.:

Synonyms:(2S,4S)-1-acetyl-2-phenylcarbamoyl-4-pyrrolidinyl acetate

Suppliers and Price of (2S,4S)-1-acetyl-2-phenylcarbamoyl-4-pyrrolidinyl acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,4S)-1-acetyl-2-phenylcarbamoyl-4-pyrrolidinyl acetate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,4S)-1-acetyl-2-phenylcarbamoyl-4-pyrrolidinyl acetate

There total 7 articles about (2S,4S)-1-acetyl-2-phenylcarbamoyl-4-pyrrolidinyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 108-24-7
acetic anhydride

: 77937-78-1
(2S,4S)-2-phenylcarbamoyl-4-pyrrolidinyl acetate

: 77937-79-2
(2S,4S)-1-acetyl-2-phenylcarbamoyl-4-pyrrolidinyl acetate

Guidance literature:: With pyridine;
DOI:10.1246/cl.1981.165

Reference yield:

: 77937-76-9
(2S,4S)-4-acetoxy-1-benzyloxycarbonylproline

: 77937-79-2
(2S,4S)-1-acetyl-2-phenylcarbamoyl-4-pyrrolidinyl acetate

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) N-methylmorpholine, pivaloyl chloride / 1.) THF, from -45 deg C to RT, 1 h, 2.) THF, RT, 4 h

2: 100 percent / H₂ / 10percent Pd/C / methanol

3: 90 percent / pyridine, 4-(dimethylamino)pyridine / CH₂Cl₂ / Ambient temperature

With 4-methyl-morpholine; pyridine; dmap; hydrogen; pivaloyl chloride; palladium on activated charcoal; In methanol; dichloromethane;
DOI:10.1246/bcsj.55.3277

Reference yield:

: 77937-77-0
(2S,4S)-2-phenylcarbamoyl-1-benzyloxycarbonyl-4-pyrrolidinyl acetate

: 77937-79-2
(2S,4S)-1-acetyl-2-phenylcarbamoyl-4-pyrrolidinyl acetate

Guidance literature:: Multi-step reaction with 2 steps

1: 100 percent / H₂ / 10percent Pd/C / methanol

2: 90 percent / pyridine, 4-(dimethylamino)pyridine / CH₂Cl₂ / Ambient temperature

With pyridine; dmap; hydrogen; palladium on activated charcoal; In methanol; dichloromethane;
DOI:10.1246/bcsj.55.3277