Technology Process of 1,2-bis(4-(tert-butyl)phenyl)ethan-1-one
There total 14 articles about 1,2-bis(4-(tert-butyl)phenyl)ethan-1-one which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
acetic acid; zinc;
at 100 ℃;
for 19h;
Inert atmosphere;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 90 percent / PCl5 / petroleum ether / 24 h / Ambient temperature
2: 45 percent / copper powder / toluene / 24 h / 95 - 100 °C
3: N,N-dimethylaniline / 24 h / Heating; or KOH in dioxane, reflux
4: 1.) HgSO2, conc. H2SO4, 2.) water / acetic acid / 1.) reflux, 20 min, 2.) reflux, 2 h
With
phosphorus pentachloride; sulfuric acid; water; copper; N,N-dimethyl-aniline;
In
acetic acid; toluene; Petroleum ether;
DOI:10.1021/jo00336a013
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 80 percent / di-tert-butyl peroxide / 4 h / 155 to 180 deg C
2: bromine / Ambient temperature; Irradiation
3: N,N-dimethylaniline / 24 h / Heating; or KOH in dioxane, reflux, 4 h
4: bromine / CCl4 / dark, cold conditions
5: N,N-dimethylaniline / 24 h / Heating; or KOH in dioxane, reflux
6: 1.) HgSO2, conc. H2SO4, 2.) water / acetic acid / 1.) reflux, 20 min, 2.) reflux, 2 h
With
di-tert-butyl peroxide; sulfuric acid; water; bromine; N,N-dimethyl-aniline;
In
tetrachloromethane; acetic acid;
DOI:10.1021/jo00336a013
