2-Linoleoylglycerol

Base Information

Chemical Name:2-Linoleoylglycerol
CAS No.:3443-82-1
Molecular Formula:C₂₁H₃₈O₄
Molecular Weight:354.53
Hs Code.:
UNII:7OVH75512R
DSSTox Substance ID:DTXSID301016998
Nikkaji Number:J116.897E
Wikidata:Q27145325
Metabolomics Workbench ID:119505
Mol file:3443-82-1.mol

Synonyms:2-lino-Gl;2-linoleoyl-glycerol;2-linoleoylglycerol

Suppliers and Price of 2-Linoleoylglycerol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
2-Linoleoyl-rac-glycerol
10mg
$ 425.00

TRC
2-Linoleoyl-rac-glycerol
5mg
$ 75.00

Sigma-Aldrich
2-Linoleoylglycerol solution ~0.1M in acetonitrile, analytical standard
200ul
$ 345.00

Medical Isotopes, Inc.
2-Linoleoyl-rac-glycerol
10 mg
$ 875.00

Cayman Chemical
2-Linoleoyl Glycerol ≥95% (as a 9:1 mixture of the 2-LG and 1-LG)
10mg
$ 154.00

Cayman Chemical
2-Linoleoyl Glycerol ≥95% (as a 9:1 mixture of the 2-LG and 1-LG)
5mg
$ 88.00

Cayman Chemical
2-Linoleoyl Glycerol ≥95% (as a 9:1 mixture of the 2-LG and 1-LG)
1mg
$ 21.00

Cayman Chemical
2-Linoleoyl Glycerol ≥95% (as a 9:1 mixture of the 2-LG and 1-LG)
500μg
$ 11.00

American Custom Chemicals Corporation
2-LINOLEOYL-RAC-GLYCEROL 98.00%
100MG
$ 1732.50

American Custom Chemicals Corporation
2-LINOLEOYL-RAC-GLYCEROL 98.00%
10MG
$ 721.88

Total 62 raw suppliers

Chemical Property of 2-Linoleoylglycerol

Chemical Property:

Vapor Pressure:1.91E-11mmHg at 25°C
Melting Point:9°C
Refractive Index:1.488
Boiling Point:485 °C at 760 mmHg
PKA:13.54±0.10(Predicted)
Flash Point:157 °C
PSA：66.76000
Density:0.981 g/cm³
LogP:4.69630
Storage Temp.:?20°C
Solubility.:Chloroform (Slightly), DMF (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly)
XLogP3:5.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:18
Exact Mass:354.27700969
Heavy Atom Count:25
Complexity:346

Purity/Quality:

98%Min ^*data from raw suppliers

2-Linoleoyl-rac-glycerol ^*data from reagent suppliers

Safty Information:

Pictogram(s): F,Xn
Hazard Codes:F,Xn
Statements: 11-20/21/22-36
Safety Statements: 16-36/37

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCCC=CCC=CCCCCCCCC(=O)OC(CO)CO
Isomeric SMILES:CCCCC/C=C\C/C=C\CCCCCCCC(=O)OC(CO)CO
Uses 2-Arachidonoyl glycerol (2-AG) has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the CB1 receptor. The congener of 2-AG in which a linoleoyl group replaces the arachidonoyl group is 2-linoleoyl glycerol (2-LG), and 2-LINOLEOYL-RAC-GLYCEROL also appears in vivo in conjunction with 2-AG. Although the intrinsic activity of 2-LG is low, it potentiates the activity of other endocannabinoids, including 2-AG. This “entourage” effect has been attributed to blockade of the breakdown and reuptake pathways that normally function to reduce endocannabinoid levels rapidly upon release. A fatty acid monoglycerides in vegetable oils with medium unsaturation.

Technology Process of 2-Linoleoylglycerol

There total 6 articles about 2-Linoleoylglycerol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 402562-28-1
2-((9Z,12Z)-octadeca-9,12-dienoyloxy)propane-1,3-diyl dibutyrate

: 126392-16-3,3443-82-1
2-linoleoyl glycerol

Guidance literature:: With Rhizomucor miehei lipase; ethanol; at 20 ℃; for 24h; regiospecific reaction; Enzymatic reaction;
DOI:10.1016/j.tet.2012.04.101

Reference yield: 65.7%

: 537-40-6
1,2,3-tri(cis,cis-9,12-octadecadienoyloxy)propane

: 126392-16-3,3443-82-1
2-linoleoyl glycerol

Guidance literature:: With Novozym 435; ethanol; at 25 ℃; for 4h; Enzymatic reaction;
DOI:10.1007/s11746-012-2113-z

Reference yield:

: 7459-33-8
linoleyl chloride

: 126392-16-3,3443-82-1
2-linoleoyl glycerol

Guidance literature:: With pyridine; chloroform; Erhitzen des Reaktionsprodukts mit Triaethylborat und Borsaeure und Behandeln einer Loesung des danach isolierten Reaktionsprodukts in Aether mit Wasser;
DOI:10.1021/ja01118a004