(E)-N,N-diisopropyl-3-(2-hydroxy-5-methylphenyl)-3-phenyl-2-propenamide

Base Information

Chemical Name:(E)-N,N-diisopropyl-3-(2-hydroxy-5-methylphenyl)-3-phenyl-2-propenamide
CAS No.:1387004-83-2
Molecular Formula:C₂₂H₂₇NO₂
Molecular Weight:337.462
Hs Code.:

Synonyms:(E)-N,N-diisopropyl-3-(2-hydroxy-5-methylphenyl)-3-phenyl-2-propenamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (E)-N,N-diisopropyl-3-(2-hydroxy-5-methylphenyl)-3-phenyl-2-propenamide

Chemical Property:

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Technology Process of (E)-N,N-diisopropyl-3-(2-hydroxy-5-methylphenyl)-3-phenyl-2-propenamide

There total 6 articles about (E)-N,N-diisopropyl-3-(2-hydroxy-5-methylphenyl)-3-phenyl-2-propenamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 6627-55-0
2-bromo-p-cresol

: 23795-34-8,119163-14-3
(E)-N,N-diisopropylcinnamamide

: 1387004-83-2
(E)-N,N-diisopropyl-3-(2-hydroxy-5-methylphenyl)-3-phenyl-2-propenamide

Guidance literature:: With N-Methyldicyclohexylamine; bis(tri-t-butylphosphine)palladium⁽⁰⁾; In 2-methyltetrahydrofuran; at 80 ℃; for 4h; Product distribution / selectivity; Inert atmosphere;

Reference yield: 74.0%

: 6627-55-0
2-bromo-p-cresol

: 23795-34-8
3-phenylpropenoic acid N,N-diisopropylamide

: 1387004-83-2
(E)-N,N-diisopropyl-3-(2-hydroxy-5-methylphenyl)-3-phenyl-2-propenamide

Guidance literature:: 2-bromo-p-cresol; 3-phenylpropenoic acid N,N-diisopropylamide; With N-Methyldicyclohexylamine; bis(tri-t-butylphosphine)palladium⁽⁰⁾; In 2-methyltetrahydrofuran; at 80 ℃; for 4h; Inert atmosphere;

With hydrogenchloride; In 2-methyltetrahydrofuran; water; at 55 ℃; pH=1; Product distribution / selectivity;

Reference yield:

: 6627-55-0
2-bromo-p-cresol

: 23795-34-8,119163-14-3
(E)-N,N-diisopropylcinnamamide

: 1387004-83-2
(E)-N,N-diisopropyl-3-(2-hydroxy-5-methylphenyl)-3-phenyl-2-propenamide

: 1387004-82-1
(Z)-N,N-diisopropyl-3-(2-hydroxy-5-methylphenyl)-3-phenyl-2-propenamide

Guidance literature:: With N-Methyldicyclohexylamine; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; tri-tert-butyl phosphine; In 2-methyltetrahydrofuran; at 150 ℃; for 0.0333333h; Product distribution / selectivity; Microwave irradiation;