(S)-9-<3-hydroxy-2-<(diisopropylphosphono)methoxy>propyl>-N²-<(p-methoxyphenyl)diphenylmethyl>guanine

Base Information

• Chemical Name: (S)-9-<3-hydroxy-2-<(diisopropylphosphono)methoxy>propyl>-N²-<(p-methoxyphenyl)diphenylmethyl>guanine
• CAS No.: 151223-26-6
• Molecular Formula: C₃₅H₄₂N₅O₇P
• Molecular Weight: 675.722

Synonyms:(S)-9-<3-hydroxy-2-<(diisopropylphosphono)methoxy>propyl>-N²-<(p-methoxyphenyl)diphenylmethyl>guanine

Chemical Property of (S)-9-<3-hydroxy-2-<(diisopropylphosphono)methoxy>propyl>-N²-<(p-methoxyphenyl)diphenylmethyl>guanine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-9-<3-hydroxy-2-<(diisopropylphosphono)methoxy>propyl>-N²-<(p-methoxyphenyl)diphenylmethyl>guanine

There total 3 articles about (S)-9-<3-hydroxy-2-<(diisopropylphosphono)methoxy>propyl>-N²-<(p-methoxyphenyl)diphenylmethyl>guanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

(S)-6-O-benzyl-9-<3-(benzyloxy)-2-<(diisopropylphosphono)methoxy>propyl>-N2-<(p-methoxyphenyl)diphenylmethyl>guanine (151223-25-5) → (S)-9-<3-hydroxy-2-<(diisopropylphosphono)methoxy>propyl>-N2-<(p-methoxyphenyl)diphenylmethyl>guanine (151223-26-6)

Guidance literature:

With cyclohexene; palladium dihydroxide; In ethanol; for 14h; Heating;

DOI:10.1021/jm00071a003

Reference yield:

(R)-6-O-benzyl-9-<3-(benzyloxy)-2-<(diisopropylphosphono)methoxy>propyl>guanine (151223-24-4) → (S)-9-<3-hydroxy-2-<(diisopropylphosphono)methoxy>propyl>-N2-<(p-methoxyphenyl)diphenylmethyl>guanine (151223-26-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 81 percent / 4-(dimethylamino)pyridine, Et₃N / dimethylformamide / 20 h / 40 °C

2: 51 percent / cyclohexene / 20percent Pd(OH)2/C / ethanol / 14 h / Heating

With dmap; triethylamine; cyclohexene; palladium dihydroxide; In ethanol; N,N-dimethyl-formamide;

DOI:10.1021/jm00071a003

Reference yield:

mono-4-methoxytrityl chloride (14470-28-1) → (S)-9-<3-hydroxy-2-<(diisopropylphosphono)methoxy>propyl>-N2-<(p-methoxyphenyl)diphenylmethyl>guanine (151223-26-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 81 percent / 4-(dimethylamino)pyridine, Et₃N / dimethylformamide / 20 h / 40 °C

2: 51 percent / cyclohexene / 20percent Pd(OH)2/C / ethanol / 14 h / Heating

With dmap; triethylamine; cyclohexene; palladium dihydroxide; In ethanol; N,N-dimethyl-formamide;

DOI:10.1021/jm00071a003

upstream raw materials:

(S)-6-O-benzyl-9-<3-(benzyloxy)-2-<(diisopropylphosphono)methoxy>propyl>-N²-<(p-methoxyphenyl)diphenylmethyl>guanine

(R)-6-O-benzyl-9-<3-(benzyloxy)-2-<(diisopropylphosphono)methoxy>propyl>guanine

mono-4-methoxytrityl chloride

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 151223-26-6 (S)-9-<3-hydroxy-2-<(diisopropylphosphono)methoxy>propyl>-N²-<(p-methoxyphenyl)diphenylmethyl>guanine

Send

Send

Metric Ton KG G Pound L ML

Send

Send