3-[6-(3,4-Dimethoxy-phenyl)-5,6,7,8-tetrahydro-quinolin-6-yl]-propionic acid hydrazide

Base Information

Chemical Name:3-[6-(3,4-Dimethoxy-phenyl)-5,6,7,8-tetrahydro-quinolin-6-yl]-propionic acid hydrazide
CAS No.:79477-48-8
Molecular Formula:C₂₀H₂₅N₃O₃
Molecular Weight:355.437
Hs Code.:

Synonyms:3-[6-(3,4-Dimethoxy-phenyl)-5,6,7,8-tetrahydro-quinolin-6-yl]-propionic acid hydrazide

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Chemical Property of 3-[6-(3,4-Dimethoxy-phenyl)-5,6,7,8-tetrahydro-quinolin-6-yl]-propionic acid hydrazide

Chemical Property:

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Technology Process of 3-[6-(3,4-Dimethoxy-phenyl)-5,6,7,8-tetrahydro-quinolin-6-yl]-propionic acid hydrazide

There total 4 articles about 3-[6-(3,4-Dimethoxy-phenyl)-5,6,7,8-tetrahydro-quinolin-6-yl]-propionic acid hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 79477-47-7
3-[6-(3,4-Dimethoxy-phenyl)-5,6,7,8-tetrahydro-quinolin-6-yl]-propionic acid ethyl ester

: 79477-48-8
3-[6-(3,4-Dimethoxy-phenyl)-5,6,7,8-tetrahydro-quinolin-6-yl]-propionic acid hydrazide

Guidance literature:: With hydrazine hydrate; In ethanol;

Reference yield:

: 79477-44-4
6-(3,4-Dimethoxy-phenyl)-5,6,7,8-tetrahydro-quinoline-6-carbonitrile

: 79477-48-8
3-[6-(3,4-Dimethoxy-phenyl)-5,6,7,8-tetrahydro-quinolin-6-yl]-propionic acid hydrazide

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) di-isobutylaluminium hydride, 2.) H₂SO₄ / 1.) benzene, -5 deg C, 0.5 h,

2: 90 percent / benzene

3: H₂ / Pt / ethanol

4: 90 percent / hydrazine hydrate / ethanol

With diisobutylaluminum hydride; sulfuric acid; hydrogen; hydrazine hydrate; platinum; In ethanol; benzene;

Reference yield:

: 79477-43-3
4-Allyloxyimino-1-(3,4-dimethoxy-phenyl)-cyclohexanecarbonitrile

: 79477-48-8
3-[6-(3,4-Dimethoxy-phenyl)-5,6,7,8-tetrahydro-quinolin-6-yl]-propionic acid hydrazide

Guidance literature:: Multi-step reaction with 5 steps

1: 37 percent / air / 24 h / Heating

2: 1.) di-isobutylaluminium hydride, 2.) H₂SO₄ / 1.) benzene, -5 deg C, 0.5 h,

3: 90 percent / benzene

4: H₂ / Pt / ethanol

5: 90 percent / hydrazine hydrate / ethanol

With diisobutylaluminum hydride; air; sulfuric acid; hydrogen; hydrazine hydrate; platinum; In ethanol; benzene;