N-[4-(2-Methoxybenzoyl)-3-pyridinyl]-2,2-dimethylpropanamide

Base Information

Chemical Name:N-[4-(2-Methoxybenzoyl)-3-pyridinyl]-2,2-dimethylpropanamide
CAS No.:125867-33-6
Molecular Formula:C₁₈H₂₀N₂O₃
Molecular Weight:312.368
Hs Code.:
DSSTox Substance ID:DTXSID101183599

Synonyms:N-[4-(2-Methoxybenzoyl)-3-pyridinyl]-2,2-dimethylpropanamide;125867-33-6;SCHEMBL1643811;DTXSID101183599

Suppliers and Price of N-[4-(2-Methoxybenzoyl)-3-pyridinyl]-2,2-dimethylpropanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of N-[4-(2-Methoxybenzoyl)-3-pyridinyl]-2,2-dimethylpropanamide

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:312.14739250
Heavy Atom Count:23
Complexity:431

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)C(=O)NC1=C(C=CN=C1)C(=O)C2=CC=CC=C2OC

Technology Process of N-[4-(2-Methoxybenzoyl)-3-pyridinyl]-2,2-dimethylpropanamide

There total 4 articles about N-[4-(2-Methoxybenzoyl)-3-pyridinyl]-2,2-dimethylpropanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 125867-33-6
(2-methoxyphenyl) (3-pivaloylamino-4-pyridyl) ketone

Guidance literature:

Reference yield: 95.0%

: 82791-72-8
(2-methoxyphenyl)(3-pivaloylamino-4-pyridyl)methanol

: 125867-33-6
(2-methoxyphenyl) (3-pivaloylamino-4-pyridyl) ketone

Guidance literature:: With manganese(IV) oxide; In toluene; for 3h; Heating;
DOI:10.1002/jhet.5570260119

Reference yield:

: 70298-88-3
N-(pyridin-3-yl)pivalamide

: 125867-33-6
(2-methoxyphenyl) (3-pivaloylamino-4-pyridyl) ketone

Guidance literature:: Multi-step reaction with 2 steps

1: 50 percent / 1.) n-BuLi/TMEDA / diethyl ether; hexane; tetrahydrofuran / 1.) -10 degC, 2 h, 2.) 0 degC, 2 h

2: 95 percent / MnO₂ / toluene / 3 h / Heating

With manganese(IV) oxide; n-butyllithium; N,N,N,N,-tetramethylethylenediamine; In tetrahydrofuran; diethyl ether; hexane; toluene;
DOI:10.1002/jhet.5570260119