10-Methoxy-4-(2-methoxy-phenyl)-6H-benzo[c]chromene

Base Information

• Chemical Name: 10-Methoxy-4-(2-methoxy-phenyl)-6H-benzo[c]chromene
• CAS No.: 141957-81-5
• Molecular Formula: C₂₁H₁₈O₃
• Molecular Weight: 318.372
• Mol file: 141957-81-5.mol

Synonyms:10-Methoxy-4-(2-methoxy-phenyl)-6H-benzo[c]chromene

Chemical Property of 10-Methoxy-4-(2-methoxy-phenyl)-6H-benzo[c]chromene

Chemical Property:

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Technology Process of 10-Methoxy-4-(2-methoxy-phenyl)-6H-benzo[c]chromene

There total 4 articles about 10-Methoxy-4-(2-methoxy-phenyl)-6H-benzo[c]chromene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

4-iodoanisol (529-28-2) → 10-Methoxy-4-(2-methoxy-phenyl)-6H-benzo[c]chromene (141957-81-5)

Guidance literature:

With palladium diacetate; tetrabutylammomium bromide; potassium carbonate; In N,N-dimethyl-formamide; at 100 ℃; for 72h;

Reference yield: 64.0%

4-iodoanisol (529-28-2) → 10-Methoxy-4-(2-methoxy-phenyl)-6H-benzo[c]chromene (141957-81-5) + 2,2',2''-trimethoxy-1,1:3',1''-terphenyl (83604-34-6) + 2,6-bis(o-methoxyphenyl)phenol

Guidance literature:

With n-Bu₄Br; phenantroline; potassium carbonate; palladium diacetate; In N,N-dimethyl-formamide; at 100 ℃; for 72h; Product distribution; other reag.; other catalyst; other solvent;

DOI:10.1016/S0022-328X(98)00384-2

Reference yield: 21.0%

2-methyl-1-propenylbromide (3017-69-4) + 4-iodoanisol (529-28-2) → 3-(1-Methylethyl)benzofuran (33118-70-6) + 10-Methoxy-4-(2-methoxy-phenyl)-6H-benzo[c]chromene (141957-81-5) + 2,3-Dihydro-3-(1-methylethylidene)benzofuran + 3-(1-Methylethyl)-7-(2-methylpropen-1-yl)benzofuran

Guidance literature:

With tetrabutylammomium bromide; potassium carbonate; palladium diacetate; In N,N-dimethyl-formamide; at 100 ℃; for 72h; Further byproducts given;

DOI:10.1021/jo00075a044

upstream raw materials:

2-methyl-1-propenylbromide

4-iodoanisol