2-imino-3-(2'-nitrophenyl)-thiazolidine hydrochloride

Base Information

• Chemical Name: 2-imino-3-(2'-nitrophenyl)-thiazolidine hydrochloride
• CAS No.: 100417-25-2
• Molecular Formula: C₉H₉N₃O₂S*ClH
• Molecular Weight: 259.716
• Mol file: 100417-25-2.mol

Synonyms:2-imino-3-(2'-nitrophenyl)-thiazolidine hydrochloride

Chemical Property of 2-imino-3-(2'-nitrophenyl)-thiazolidine hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-imino-3-(2'-nitrophenyl)-thiazolidine hydrochloride

There total 4 articles about 2-imino-3-(2'-nitrophenyl)-thiazolidine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

2-nitro-N-(2-thiocyanatoethyl)-aniline (100418-44-8) → 2-imino-3-(2'-nitrophenyl)-thiazolidine hydrochloride (100417-25-2)

Guidance literature:

With hydrogenchloride; In ethanol; Heating;

DOI:10.1016/S0040-4020(01)89768-4

Reference yield:

2-aminodihydrothiazole (50283-09-5) + ortho-nitrofluorobenzene (1493-27-2,127723-77-7) → 2-imino-3-(2'-nitrophenyl)-thiazolidine hydrochloride (100417-25-2)

Guidance literature:

With dimethyl sulfoxide; In water;

Reference yield:

2-[(2-nitrophenyl)amino]ethanol (4926-55-0) → 2-imino-3-(2'-nitrophenyl)-thiazolidine hydrochloride (100417-25-2)

Guidance literature:

Multi-step reaction with 3 steps

1: 91 percent / pyridine / Ambient temperature

2: 85 percent / Heating

3: 83 percent / HCl gas / ethanol / Heating

With pyridine; hydrogenchloride; In ethanol;

DOI:10.1016/S0040-4020(01)89768-4

upstream raw materials:

2-nitro-N-(2-thiocyanatoethyl)-aniline

2-[(2-nitrophenyl)amino]ethanol

2-((2-nitrophenyl)amino)ethyl methanesulfonate

2-aminodihydrothiazole

Refernces

• 1、 -. "Iminothiazolidine derivatives". . . Retrieved 2008/06/13.