C₂₁H₂₀F₃N₃O₂

Base Information

Chemical Name:C₂₁H₂₀F₃N₃O₂
CAS No.:1416892-61-9
Molecular Formula:C₂₁H₂₀F₃N₃O₂
Molecular Weight:403.404
Hs Code.:

C<sub>21</sub>H<sub>20</sub>F<sub>3</sub>N<sub>3</sub>O<sub>2</sub>

Synonyms:C₂₁H₂₀F₃N₃O₂

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₂₁H₂₀F₃N₃O₂

Chemical Property:

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Technology Process of C₂₁H₂₀F₃N₃O₂

There total 6 articles about C₂₁H₂₀F₃N₃O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1416891-98-9
2,2,2-trifluoro-1-[4-[1-(4-nitrophenyl)indol-3-yl]-3,6-dihydro-2H-pyridin-1-yl]ethanone

: 1416892-61-9
C₂₁H₂₀F₃N₃O₂

Guidance literature:: With borane-THF; In tetrahydrofuran; for 18h; Reflux;

Reference yield:

: 120-72-9
indole

: 1416892-61-9
C₂₁H₂₀F₃N₃O₂

Guidance literature:: Multi-step reaction with 5 steps

1: potassium hydroxide / methanol / 18 h / 60 °C

2: caesium carbonate / N,N-dimethyl-formamide / 18 h / 40 °C

3: trifluoroacetic acid / dichloromethane / 1 h / 20 °C

4: triethylamine / dichloromethane / 72 h / 20 °C

5: borane-THF / tetrahydrofuran / 18 h / Reflux

With borane-THF; caesium carbonate; triethylamine; trifluoroacetic acid; potassium hydroxide; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: 155302-27-5
3-[N-(t-butyloxycarbonyl)-1,2,3,6-tetrahydropyridin-4-yl]-1H-indole

: 1416892-61-9
C₂₁H₂₀F₃N₃O₂

Guidance literature:: Multi-step reaction with 4 steps

1: caesium carbonate / N,N-dimethyl-formamide / 18 h / 40 °C

2: trifluoroacetic acid / dichloromethane / 1 h / 20 °C

3: triethylamine / dichloromethane / 72 h / 20 °C

4: borane-THF / tetrahydrofuran / 18 h / Reflux

With borane-THF; caesium carbonate; triethylamine; trifluoroacetic acid; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;