Technology Process of 5-chloro-2-(2-methylbenzyl)aniline
There total 4 articles about 5-chloro-2-(2-methylbenzyl)aniline which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
iron; acetic acid;
In
ethanol;
at 90 ℃;
for 0.833333h;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: boron dimethyl-trifluoro sulphide / tetrahydrofuran / 0 - 60 °C / Inert atmosphere
2: phosphorus tribromide / toluene / 0.25 h / 100 °C
3: potassium carbonate / palladium dichloride / water; acetone / 1.17 h / 20 °C / Inert atmosphere
4: acetic acid; iron / ethanol / 0.83 h / 90 °C
With
boron dimethyl-trifluoro sulphide; phosphorus tribromide; iron; potassium carbonate; acetic acid;
palladium dichloride;
In
tetrahydrofuran; ethanol; water; acetone; toluene;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: phosphorus tribromide / toluene / 0.25 h / 100 °C
2: potassium carbonate / palladium dichloride / water; acetone / 1.17 h / 20 °C / Inert atmosphere
3: acetic acid; iron / ethanol / 0.83 h / 90 °C
With
phosphorus tribromide; iron; potassium carbonate; acetic acid;
palladium dichloride;
In
ethanol; water; acetone; toluene;
