4-[3-[(2-Bromophenyl)methyl]-2-methyl-2-oxazolidinyl]pyridine

Base Information

Chemical Name:4-[3-[(2-Bromophenyl)methyl]-2-methyl-2-oxazolidinyl]pyridine
CAS No.:251326-36-0
Molecular Formula:C₁₆H₁₇BrN₂O
Molecular Weight:333.228
Hs Code.:
DSSTox Substance ID:DTXSID001183091

Synonyms:DTXSID001183091;4-[3-[(2-Bromophenyl)methyl]-2-methyl-2-oxazolidinyl]pyridine;251326-36-0

Suppliers and Price of 4-[3-[(2-Bromophenyl)methyl]-2-methyl-2-oxazolidinyl]pyridine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-[3-[(2-Bromophenyl)methyl]-2-methyl-2-oxazolidinyl]pyridine

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:332.05243
Heavy Atom Count:20
Complexity:322

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1(N(CCO1)CC2=CC=CC=C2Br)C3=CC=NC=C3

Technology Process of 4-[3-[(2-Bromophenyl)methyl]-2-methyl-2-oxazolidinyl]pyridine

There total 2 articles about 4-[3-[(2-Bromophenyl)methyl]-2-methyl-2-oxazolidinyl]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 1122-54-9
methyl (4-pyridyl) ketone

: 251326-32-6
2-((2-bromobenzyl)amino)ethan-1-ol

: 251326-36-0
4-(3-(2-bromobenzyl)-2-methyloxazolidin-2-yl)pyridine

Guidance literature:: With p-toluenesulfonic acid monohydrate; In benzene; for 6h; Heating;
DOI:10.1016/S0040-4020(00)01123-6

Reference yield:

: 6630-33-7
ortho-bromobenzaldehyde

: 251326-36-0
4-(3-(2-bromobenzyl)-2-methyloxazolidin-2-yl)pyridine

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium carbonate / ethanol / 1 h / Heating

1.2: 89 percent / sodium borohydride / ethanol / 3 h / 20 °C

2.1: 72 percent / 4-toluenesulfonic acid monohydrate / benzene / 6 h / Heating

With p-toluenesulfonic acid monohydrate; potassium carbonate; In ethanol; benzene;
DOI:10.1016/S0040-4020(00)01123-6