3,6-Dihydro-1,1-dioxydo-4-methyl-2-phenyl 2H-thiopyrane

Base Information

• Chemical Name: 3,6-Dihydro-1,1-dioxydo-4-methyl-2-phenyl 2H-thiopyrane
• CAS No.: 100420-76-6
• Molecular Formula: C₁₂H₁₄O₂S
• Molecular Weight: 222.308
• Mol file: 100420-76-6.mol

Synonyms:3,6-Dihydro-1,1-dioxydo-4-methyl-2-phenyl 2H-thiopyrane

Chemical Property of 3,6-Dihydro-1,1-dioxydo-4-methyl-2-phenyl 2H-thiopyrane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,6-Dihydro-1,1-dioxydo-4-methyl-2-phenyl 2H-thiopyrane

There total 5 articles about 3,6-Dihydro-1,1-dioxydo-4-methyl-2-phenyl 2H-thiopyrane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

(1R,2S)-4-Methyl-2-phenyl-3,6-dihydro-2H-thiopyran 1-oxide (100420-64-2,100420-75-5) → 3,6-Dihydro-1,1-dioxydo-4-methyl-2-phenyl 2H-thiopyrane (100420-76-6)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at -78 - 15 ℃;

DOI:10.1016/S0040-4039(00)98128-0

Reference yield: 82.0%

3,6-Dihydro-4-methyl-1α-oxydo-2β-phenyl 2H-thiopyrane (100420-64-2,100420-75-5) → 3,6-Dihydro-1,1-dioxydo-4-methyl-2-phenyl 2H-thiopyrane (100420-76-6)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; -78 deg C to ambient temperature;

Reference yield:

4-Methyl-2-phenyl-3,6-dihydro-2H-thiopyran (87362-82-1) → 3,6-Dihydro-1,1-dioxydo-4-methyl-2-phenyl 2H-thiopyrane (100420-76-6)

Guidance literature:

Multi-step reaction with 2 steps

1: m-CPBA / CH₂Cl₂ / -78 - 15 °C

2: 82 percent / m-CPBA / CH₂Cl₂ / -78 - 15 °C

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane;

DOI:10.1016/S0040-4039(00)98128-0

upstream raw materials:

3,6-Dihydro-4-methyl-1α-oxydo-2β-phenyl 2H-thiopyrane

(1R,2S)-4-Methyl-2-phenyl-3,6-dihydro-2H-thiopyran 1-oxide

((Z)-3-Methyl-buta-1,3-dienylsulfanylmethyl)-benzene

4-Methyl-2-phenyl-3,6-dihydro-2H-thiopyran

Refernces

• 1、 Reglier, Marius,Julia, Sylvestre A.. "STEREOSPECIFIC CYCLISATIONS OF SUBSTITUTED α'-LITHIATED α(Z),γ-BUTADIENYL SULFOXIDES". . p. 2655 - 2658. Retrieved 2007/10/02.