Technology Process of C27H34O3Si
There total 7 articles about C27H34O3Si which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
potassium trimethylsilonate;
In
tetrahydrofuran; diethyl ether;
at 45 ℃;
for 13h;
DOI:10.1021/ol103024z
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: lithium aluminium tetrahydride / tetrahydrofuran / 0.5 h / 0 °C
2.1: 1H-imidazole / dichloromethane / 2 h / 0 °C
3.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.33 h / -78 °C
3.2: 0.5 h / -78 °C
4.1: potassium hexamethylsilazane / 1,2-dimethoxyethane / -78 °C
5.1: palladium diacetate; triethylamine; tris-(o-tolyl)phosphine / methanol / 1 h / Inert atmosphere; Reflux
6.1: potassium trimethylsilonate / tetrahydrofuran; diethyl ether / 13 h / 45 °C
With
1H-imidazole; lithium aluminium tetrahydride; oxalyl dichloride; potassium trimethylsilonate; palladium diacetate; potassium hexamethylsilazane; dimethyl sulfoxide; triethylamine; tris-(o-tolyl)phosphine;
In
tetrahydrofuran; methanol; 1,2-dimethoxyethane; diethyl ether; dichloromethane;
3.1: Swern oxidation / 3.2: Swern oxidation / 4.1: Horner-Wadsworth-Emmons olefination / 5.1: Mizoroki-Heck cyclization;
DOI:10.1021/ol103024z
- Guidance literature:
-
Multi-step reaction with 3 steps
1: potassium hexamethylsilazane / 1,2-dimethoxyethane / -78 °C
2: palladium diacetate; triethylamine; tris-(o-tolyl)phosphine / methanol / 1 h / Inert atmosphere; Reflux
3: potassium trimethylsilonate / tetrahydrofuran; diethyl ether / 13 h / 45 °C
With
potassium trimethylsilonate; palladium diacetate; potassium hexamethylsilazane; triethylamine; tris-(o-tolyl)phosphine;
In
tetrahydrofuran; methanol; 1,2-dimethoxyethane; diethyl ether;
1: Horner-Wadsworth-Emmons olefination / 2: Mizoroki-Heck cyclization;
DOI:10.1021/ol103024z
