(R)-quinuclidin-3-yl 2-(2,4-dimethylthiazole-5-sulfonamido)-2-phenylacetate

Base Information

Chemical Name:(R)-quinuclidin-3-yl 2-(2,4-dimethylthiazole-5-sulfonamido)-2-phenylacetate
CAS No.:1379513-93-5
Molecular Formula:C₂₀H₂₅N₃O₄S₂
Molecular Weight:435.568
Hs Code.:

Synonyms:(R)-quinuclidin-3-yl 2-(2,4-dimethylthiazole-5-sulfonamido)-2-phenylacetate

Suppliers and Price of (R)-quinuclidin-3-yl 2-(2,4-dimethylthiazole-5-sulfonamido)-2-phenylacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (R)-quinuclidin-3-yl 2-(2,4-dimethylthiazole-5-sulfonamido)-2-phenylacetate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R)-quinuclidin-3-yl 2-(2,4-dimethylthiazole-5-sulfonamido)-2-phenylacetate

There total 8 articles about (R)-quinuclidin-3-yl 2-(2,4-dimethylthiazole-5-sulfonamido)-2-phenylacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.2%

: [(3R)-quinuclidin-3-yl]2-amino-2-phenylacetate bis hydrochloride salt

: 80466-80-4
2,4-dimethyl-1,3-thiazol-5-sulfonylchloride

: 1379513-93-5
(R)-quinuclidin-3-yl 2-(2,4-dimethylthiazole-5-sulfonamido)-2-phenylacetate

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 3h;

Reference yield:

: 2900-27-8,3601-66-9,14675-97-9,33125-05-2
2-(tert-butoxycarbonylamino)-2-phenylacetic acid

: 1379513-93-5
(R)-quinuclidin-3-yl 2-(2,4-dimethylthiazole-5-sulfonamido)-2-phenylacetate

Guidance literature:: Multi-step reaction with 3 steps

1: dicyclohexyl-carbodiimide; benzotriazol-1-ol / tetrahydrofuran / 20 °C

2: hydrogenchloride / water; tetrahydrofuran / 15 h / 20 °C

3: triethylamine / dichloromethane / 3 h / 20 °C

With hydrogenchloride; benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide; In tetrahydrofuran; dichloromethane; water;

Reference yield:

: 2835-06-5
phenylglycin

: 1379513-93-5
(R)-quinuclidin-3-yl 2-(2,4-dimethylthiazole-5-sulfonamido)-2-phenylacetate

Guidance literature:: Multi-step reaction with 4 steps

1.1: sodium hydroxide / water; acetone / 1 h / 20 °C

1.2: pH 5

2.1: dicyclohexyl-carbodiimide; benzotriazol-1-ol / tetrahydrofuran / 20 °C

3.1: hydrogenchloride / water; tetrahydrofuran / 15 h / 20 °C

4.1: triethylamine / dichloromethane / 3 h / 20 °C

With hydrogenchloride; benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide; sodium hydroxide; In tetrahydrofuran; dichloromethane; water; acetone;