C₂₂H₂₁BrN₂

Base Information

• Chemical Name: C₂₂H₂₁BrN₂
• CAS No.: 1435946-31-8
• Molecular Formula: C₂₂H₂₁BrN₂
• Molecular Weight: 393.326
• Mol file: 1435946-31-8.mol

Synonyms:C₂₂H₂₁BrN₂

Chemical Property of C₂₂H₂₁BrN₂

Chemical Property:

Purity/Quality:

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• Pictogram(s):  
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MSDS Files:

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Technology Process of C₂₂H₂₁BrN₂

There total 2 articles about C₂₂H₂₁BrN₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

C24H25BrN2O3 (1437311-55-1) → C22H21BrN2 (1435946-31-8)

Guidance literature:

With propylamine; potassium phosphate; bis(1,5-cyclooctadiene)diiridium(I) dichloride; N-benzhydryl-N-phenyldinaphthophosphoramidite; In tetrahydrofuran; at 50 ℃; for 48h; enantioselective reaction; Schlenk technique; Inert atmosphere;

DOI:10.1021/ja403535a

Reference yield:

C18H17BrN2 (1437311-80-2) → C22H21BrN2 (1435946-31-8)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / tetrahydrofuran / 0 - 20 °C / Inert atmosphere

2: bis(1,5-cyclooctadiene)diiridium(I) dichloride; N-benzhydryl-N-phenyldinaphthophosphoramidite; potassium phosphate; propylamine / tetrahydrofuran / 48 h / 50 °C / Schlenk technique; Inert atmosphere

With propylamine; potassium phosphate; bis(1,5-cyclooctadiene)diiridium(I) dichloride; N-benzhydryl-N-phenyldinaphthophosphoramidite; triethylamine; In tetrahydrofuran;

DOI:10.1021/ja403535a

upstream raw materials:

C₁₈H₁₇BrN₂

C₂₄H₂₅BrN₂O₃