N-(tert-butyloxycarbonyl)-N-(3-methyl-but-2-enyl)-2,4,6-trimethylphenylamine

Base Information

• Chemical Name: N-(tert-butyloxycarbonyl)-N-(3-methyl-but-2-enyl)-2,4,6-trimethylphenylamine
• CAS No.: 437613-71-3
• Molecular Formula: C₁₉H₂₉NO₂
• Molecular Weight: 303.445
• Mol file: 437613-71-3.mol

Synonyms:N-(tert-butyloxycarbonyl)-N-(3-methyl-but-2-enyl)-2,4,6-trimethylphenylamine

Chemical Property of N-(tert-butyloxycarbonyl)-N-(3-methyl-but-2-enyl)-2,4,6-trimethylphenylamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(tert-butyloxycarbonyl)-N-(3-methyl-but-2-enyl)-2,4,6-trimethylphenylamine

There total 3 articles about N-(tert-butyloxycarbonyl)-N-(3-methyl-but-2-enyl)-2,4,6-trimethylphenylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

(2,4,6-trimethyl-phenyl)-carbamic acid tert-butyl ester (56700-69-7) + prenyl bromide (870-63-3) → N-(tert-butyloxycarbonyl)-N-(3-methyl-but-2-enyl)-2,4,6-trimethylphenylamine (437613-71-3)

Guidance literature:

(2,4,6-trimethyl-phenyl)-carbamic acid tert-butyl ester; With potassium hydride; In N,N-dimethyl-formamide; at 0 - 22 ℃;

prenyl bromide; In N,N-dimethyl-formamide; at 22 ℃; for 1h; Further stages.;

DOI:10.1021/ja020259c

Reference yield:

di-tert-butyl dicarbonate (24424-99-5) → N-(tert-butyloxycarbonyl)-N-(3-methyl-but-2-enyl)-2,4,6-trimethylphenylamine (437613-71-3)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 98 percent / tetrahydrofuran / 168 h / Heating

2.1: KH / dimethylformamide / 0 - 22 °C

2.2: 90 percent / dimethylformamide / 1 h / 22 °C

With potassium hydride; In tetrahydrofuran; N,N-dimethyl-formamide;

DOI:10.1021/ja020259c

Reference yield:

2,4,6-trimethylaniline (88-05-1) → N-(tert-butyloxycarbonyl)-N-(3-methyl-but-2-enyl)-2,4,6-trimethylphenylamine (437613-71-3)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 98 percent / tetrahydrofuran / 168 h / Heating

2.1: KH / dimethylformamide / 0 - 22 °C

2.2: 90 percent / dimethylformamide / 1 h / 22 °C

With potassium hydride; In tetrahydrofuran; N,N-dimethyl-formamide;

DOI:10.1021/ja020259c

upstream raw materials:

(2,4,6-trimethyl-phenyl)-carbamic acid tert-butyl ester

prenyl bromide

di-tert-butyl dicarbonate

2,4,6-trimethylaniline

Downstream raw materials:

N-(tert-butyloxycarbonyl)-N-(formylmethyl)-2,4,6-trimethylphenylamine