1-phenyldodecyl acetate

Base Information

• Chemical Name: 1-phenyldodecyl acetate
• CAS No.: 125653-73-8
• Molecular Formula: C₂₀H₃₂O₂
• Molecular Weight: 304.473
• Mol file: 125653-73-8.mol

Synonyms:1-phenyldodecyl acetate

Chemical Property of 1-phenyldodecyl acetate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 1-phenyldodecyl acetate

There total 2 articles about 1-phenyldodecyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.5%

1-phenyldodecan-1-ol (1851-93-0) + acetic anhydride (108-24-7) → 1-phenyldodecyl acetate (125653-73-8)

Guidance literature:

With Amberlist 15; at 25 ℃; for 0.5h;

DOI:10.1016/j.tetasy.2011.07.017

Reference yield:

dodecanophenone (1674-38-0) → 1-phenyldodecyl acetate (125653-73-8)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium tetrahydroborate / tetrahydrofuran; methanol / 0 - 5 °C

2: Amberlist 15 / 0.5 h / 25 °C

With sodium tetrahydroborate; In tetrahydrofuran; methanol;

DOI:10.1016/j.tetasy.2011.07.017

Reference yield:

1-phenyldodecyl acetate (125653-73-8) → (R)-1-phenyl-1-dodecanol (270076-47-6)

Guidance literature:

With Burkholderica cepacia amano lipase; In acetone; at 25 ℃; pH=7.2; optical yield given as %ee; enantioselective reaction; aq. phosphate buffer; Enzymatic reaction;

DOI:10.1016/j.tetasy.2011.07.017

upstream raw materials:

1-phenyldodecan-1-ol

acetic anhydride

dodecanophenone

Downstream raw materials:

(R)-1-phenyl-1-dodecanol

(S)-1-phenyl-1-dodecanol

Refernces

• 1、 Yildiz, Tuelay,Yusufolu, Aye. "Synthesis of new (R)-secondary carbinols with different structures via enzymatic resolution". experimental part. p. 1347 - 1352. Retrieved 2011/11/29.