C₃₅H₃₈N₂O₆S

Base Information

• Chemical Name: C₃₅H₃₈N₂O₆S
• CAS No.: 946063-87-2
• Molecular Formula: C₃₅H₃₈N₂O₆S
• Molecular Weight: 614.763
• Mol file: 946063-87-2.mol

Synonyms:C₃₅H₃₈N₂O₆S

Chemical Property of C₃₅H₃₈N₂O₆S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₅H₃₈N₂O₆S

There total 1 articles about C₃₅H₃₈N₂O₆S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

trityl chloride (76-83-5) → C35H38N2O6S (946063-87-2)

Guidance literature:

Multi-step reaction with 2 steps

1: Et₃N / CH₂Cl₂ / 75 h / 20 °C

2: 75 percent / DEAD; PPh₃ / tetrahydrofuran / 20 °C

With triethylamine; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; dichloromethane; 2: Mitsunobu reaction;

DOI:10.1016/j.tetlet.2007.05.064

Reference yield:

C35H38N2O6S (946063-87-2) → (S)-1-methoxycarbonyl-2-(tolyl-4'-sulfonylamino)-ethyl-amine

Guidance literature:

With thiophenol; trifluoroacetic acid; In dichloromethane; at 25 ℃; for 1h;

DOI:10.1021/ol049439c

Reference yield:

C35H38N2O6S (946063-87-2) → (S)-2-((S)-1-Benzyloxycarbonylamino-2-methyl-propyl)-1-(toluene-4-sulfonyl)-4,5-dihydro-1H-imidazole-4-carboxylic acid methyl ester

Guidance literature:

Multi-step reaction with 3 steps

1: TFA; PhSH / CH₂Cl₂ / 1 h / 25 °C

2: DIEA; HBTU; HOBt*H₂O / dimethylformamide / 8 h / pH 10

3: 74 percent / bis(triphenyl) oxodiphosphonium trifluoromethanesulfonate / CH₂Cl₂ / 0.5 h / -20 °C

With bis(triphenyl) oxodiphosphonium trifluoromethanesulfonate; benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; thiophenol; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/ol049439c

upstream raw materials:

trityl chloride

Downstream raw materials:

C₂₀H₂₈N₂O₈S

(S)-2-((R)-2-Benzyloxycarbonylamino-3-methyl-butyrylamino)-3-(toluene-4-sulfonylamino)-propionic acid methyl ester

(S)-2-((R)-2-Benzyloxycarbonylamino-3-phenyl-propionylamino)-3-(toluene-4-sulfonylamino)-propionic acid methyl ester

(S)-2-((S)-2-Benzyloxycarbonylamino-3-phenyl-propionylamino)-3-(toluene-4-sulfonylamino)-propionic acid methyl ester