Technology Process of 3-ethyl-3-phenoxyindolin-2-one
There total 5 articles about 3-ethyl-3-phenoxyindolin-2-one which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
copper(l) iodide; N-acetylglycine; potassium iodide; sodium hydroxide;
In
tert-butyl alcohol;
at 100 ℃;
for 24h;
DOI:10.1039/c2ob26110c
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium hydride / tetrahydrofuran / 2 h / 0 °C / Inert atmosphere
1.2: 24 h / 60 °C / Inert atmosphere
2.1: potassium tert-butylate / tetrahydrofuran; 1-methyl-pyrrolidin-2-one / 0.17 h / 0 °C / Inert atmosphere
2.2: 1.17 h / 0 - 10 °C / Inert atmosphere
3.1: copper(l) iodide; N-acetylglycine; potassium iodide; sodium hydroxide / tert-butyl alcohol / 24 h / 100 °C
With
copper(l) iodide; potassium tert-butylate; sodium hydride; N-acetylglycine; potassium iodide; sodium hydroxide;
In
tetrahydrofuran; 1-methyl-pyrrolidin-2-one; tert-butyl alcohol;
DOI:10.1039/c2ob26110c
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: N-Bromosuccinimide; dibenzoyl peroxide / chloroform / 8 h / 60 °C / Inert atmosphere
2.1: sodium hydride / tetrahydrofuran / 2 h / 0 °C / Inert atmosphere
2.2: 24 h / 60 °C / Inert atmosphere
3.1: potassium tert-butylate / tetrahydrofuran; 1-methyl-pyrrolidin-2-one / 0.17 h / 0 °C / Inert atmosphere
3.2: 1.17 h / 0 - 10 °C / Inert atmosphere
4.1: copper(l) iodide; N-acetylglycine; potassium iodide; sodium hydroxide / tert-butyl alcohol / 24 h / 100 °C
With
N-Bromosuccinimide; copper(l) iodide; potassium tert-butylate; sodium hydride; N-acetylglycine; potassium iodide; sodium hydroxide; dibenzoyl peroxide;
In
tetrahydrofuran; 1-methyl-pyrrolidin-2-one; chloroform; tert-butyl alcohol;
DOI:10.1039/c2ob26110c
