N-[4-Cyano-3-(trifluoroMethyl)phenyl]-2,2,2-trifluoroacetaMide

Base Information

• Chemical Name: N-[4-Cyano-3-(trifluoroMethyl)phenyl]-2,2,2-trifluoroacetaMide
• CAS No.: 1155800-45-5
• Molecular Formula: C₁₀H₄F₆N₂O
• Molecular Weight: 282.145
• Hs Code.: 2926907090
• Mol file: 1155800-45-5.mol

Synonyms:N-(4-cyano-3-(trifluoromethyl)phenyl)-2,2,2-trifluoroacetamide

Chemical Property of N-[4-Cyano-3-(trifluoroMethyl)phenyl]-2,2,2-trifluoroacetaMide

Chemical Property:

• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

N-[4-Cyano-3-(trifluoromethyl)phenyl]-2,2,2-trifluoroacetamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: N-[4-Cyano-3-(trifluoromethyl)phenyl]-2,2,2-trifluoroacetamide, is an intermediate in the synthesis of scale-up production of 4,5-diamino-2-(trifluoromethyl)benzonitrile.

Technology Process of N-[4-Cyano-3-(trifluoroMethyl)phenyl]-2,2,2-trifluoroacetaMide

There total 1 articles about N-[4-Cyano-3-(trifluoroMethyl)phenyl]-2,2,2-trifluoroacetaMide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.5%

4-amino-2-trifluoromethylbenzonitrile (654-70-6) + trifluoroacetic anhydride (407-25-0) → N-(4-cyano-3-(trifluoromethyl)phenyl)-2,2,2-trifluoroacetamide (1155800-45-5)

Guidance literature:

With potassium carbonate; In dichloromethane; at 14 - 20 ℃; for 1.5h; Inert atmosphere; Large scale reaction;

DOI:10.1021/op9000498

Reference yield: 85.0%

N-(4-cyano-3-(trifluoromethyl)phenyl)-2,2,2-trifluoroacetamide (1155800-45-5) → N-(4-cyano-2-nitro-5-(trifluoromethyl)phenyl)-2,2,2-trifluoroacetamide (1155800-48-8) + N-(4-cyano-2,6-dinitro-5-(trifluoromethyl)phenyl)-2,2,2-trifluoroacetamide (1155800-50-2)

Guidance literature:

With trifluorormethanesulfonic acid; nitric acid; In dichloromethane; water; at 20 ℃; for 20h; Large scale reaction;

DOI:10.1021/op9000498

upstream raw materials:

4-amino-2-trifluoromethylbenzonitrile

trifluoroacetic anhydride

Downstream raw materials:

N-(4-cyano-2-nitro-5-(trifluoromethyl)phenyl)-2,2,2-trifluoroacetamide

N-(4-cyano-2,6-dinitro-5-(trifluoromethyl)phenyl)-2,2,2-trifluoroacetamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1155800-45-5 N-[4-Cyano-3-(trifluoroMethyl)phenyl]-2,2,2-trifluoroacetaMide

Send

Send

Metric Ton KG G Pound L ML

Send

Send