(Z)-3-ethyl-5-((5-(4-methoxyphenyl)-1-methyl-1H-pyrrole-2-yl)methylene)oxazolidine-2,4-dithione

Base Information

• Chemical Name: (Z)-3-ethyl-5-((5-(4-methoxyphenyl)-1-methyl-1H-pyrrole-2-yl)methylene)oxazolidine-2,4-dithione
• CAS No.: 1339917-83-7
• Molecular Formula: C₁₈H₁₈N₂O₂S₂
• Molecular Weight: 358.485
• Mol file: 1339917-83-7.mol

Synonyms:(Z)-3-ethyl-5-((5-(4-methoxyphenyl)-1-methyl-1H-pyrrole-2-yl)methylene)oxazolidine-2,4-dithione

Chemical Property of (Z)-3-ethyl-5-((5-(4-methoxyphenyl)-1-methyl-1H-pyrrole-2-yl)methylene)oxazolidine-2,4-dithione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (Z)-3-ethyl-5-((5-(4-methoxyphenyl)-1-methyl-1H-pyrrole-2-yl)methylene)oxazolidine-2,4-dithione

There total 3 articles about (Z)-3-ethyl-5-((5-(4-methoxyphenyl)-1-methyl-1H-pyrrole-2-yl)methylene)oxazolidine-2,4-dithione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

5-(4-methoxyphenyl)-1-methyl-1H-pyrrole-2-carboxaldehyde (1049131-61-4) + 3-ethyloxazolidine-2,4-dithione (1339917-87-1) → (Z)-3-ethyl-5-((5-(4-methoxyphenyl)-1-methyl-1H-pyrrole-2-yl)methylene)oxazolidine-2,4-dithione (1339917-83-7)

Guidance literature:

With sodium acetate; acetic acid; Reflux;

Reference yield:

N-methylpyrrole aldehyde (1192-58-1) + 1-bromo-4-methoxy-benzene (104-92-7) → (Z)-3-ethyl-5-((5-(4-methoxyphenyl)-1-methyl-1H-pyrrole-2-yl)methylene)oxazolidine-2,4-dithione (1339917-83-7)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / palladium diacetate / ISOPROPYLAMIDE / 21 °C / Reflux; Inert atmosphere

2: sodium acetate; acetic acid / Reflux

With sodium acetate; potassium carbonate; acetic acid; palladium diacetate; In ISOPROPYLAMIDE;

Reference yield:

3-ethyl-2-thioxo-oxazolidin-4-one (10574-66-0) → (Z)-3-ethyl-5-((5-(4-methoxyphenyl)-1-methyl-1H-pyrrole-2-yl)methylene)oxazolidine-2,4-dithione (1339917-83-7)

Guidance literature:

Multi-step reaction with 2 steps

1: Lawessons reagent / toluene / Reflux

2: sodium acetate; acetic acid / Reflux

With Lawessons reagent; sodium acetate; acetic acid; In toluene;

upstream raw materials:

N-methylpyrrole aldehyde

1-bromo-4-methoxy-benzene

3-ethyl-2-thioxo-oxazolidin-4-one

5-(4-methoxyphenyl)-1-methyl-1H-pyrrole-2-carboxaldehyde